PRL Down (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with PRL Down.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with PRL Down.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with PRL Down.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with PRL Down.

Results found

Linked to

	Label	Description
	SMAD4 Gene (Entity type)	ENSG00000141646 - SMAD family member 4
	FAM169A Gene (Entity type)	ENSG00000198780 - family with sequence similarity 169 member A
	ZMYND11 Gene (Entity type)	ENSG00000015171 - zinc finger MYND-type containing 11
	COX17 Gene (Entity type)	ENSG00000138495 - cytochrome c oxidase copper chaperone COX17
	ATG5 Gene (Entity type)	ENSG00000057663 - autophagy related 5
	PRRC2C Gene (Entity type)	ENSG00000117523 - proline rich coiled-coil 2C
	WAC Gene (Entity type)	ENSG00000095787 - WW domain containing adaptor with coiled-coil
	SMAP1 Gene (Entity type)	ENSG00000112305 - small ArfGAP 1
	ARHGAP12 Gene (Entity type)	ENSG00000165322 - Rho GTPase activating protein 12
	DUSP12 Gene (Entity type)	ENSG00000081721 - dual specificity phosphatase 12

SMAD4

Gene (Entity type)

ENSG00000141646 - SMAD family member 4

FAM169A

Gene (Entity type)

ENSG00000198780 - family with sequence similarity 169 member A

ZMYND11

Gene (Entity type)

ENSG00000015171 - zinc finger MYND-type containing 11

COX17

Gene (Entity type)

ENSG00000138495 - cytochrome c oxidase copper chaperone COX17

ATG5

Gene (Entity type)

ENSG00000057663 - autophagy related 5

PRRC2C

Gene (Entity type)

ENSG00000117523 - proline rich coiled-coil 2C

WAC

Gene (Entity type)

ENSG00000095787 - WW domain containing adaptor with coiled-coil

SMAP1

Gene (Entity type)

ENSG00000112305 - small ArfGAP 1

ARHGAP12

Gene (Entity type)

ENSG00000165322 - Rho GTPase activating protein 12

DUSP12

Gene (Entity type)

ENSG00000081721 - dual specificity phosphatase 12

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Community

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.