SIRT7 Down (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with SIRT7 Down.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with SIRT7 Down.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with SIRT7 Down.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with SIRT7 Down.

Results found

Linked to

	Label	Description
	COQ2 Gene (Entity type)	ENSG00000173085 - coenzyme Q2, polyprenyltransferase
	BSCL2 Gene (Entity type)	ENSG00000168000 - BSCL2 lipid droplet biogenesis associated, seipin
	DICER1 Gene (Entity type)	ENSG00000100697 - dicer 1, ribonuclease III
	FBXL7 Gene (Entity type)	ENSG00000183580 - F-box and leucine rich repeat protein 7
	GRHPR Gene (Entity type)	ENSG00000137106 - glyoxylate and hydroxypyruvate reductase
	HERC2 Gene (Entity type)	ENSG00000128731 - HECT and RLD domain containing E3 ubiquitin protein ligase 2
	TMEM147 Gene (Entity type)	ENSG00000105677 - transmembrane protein 147
	WDR45B Gene (Entity type)	ENSG00000141580 - WD repeat domain 45B
	DEAF1 Gene (Entity type)	ENSG00000177030 - DEAF1 transcription factor

COQ2

Gene (Entity type)

ENSG00000173085 - coenzyme Q2, polyprenyltransferase

BSCL2

Gene (Entity type)

ENSG00000168000 - BSCL2 lipid droplet biogenesis associated, seipin

DICER1

Gene (Entity type)

ENSG00000100697 - dicer 1, ribonuclease III

FBXL7

Gene (Entity type)

ENSG00000183580 - F-box and leucine rich repeat protein 7

GRHPR

Gene (Entity type)

ENSG00000137106 - glyoxylate and hydroxypyruvate reductase

HERC2

Gene (Entity type)

ENSG00000128731 - HECT and RLD domain containing E3 ubiquitin protein ligase 2

TMEM147

Gene (Entity type)

ENSG00000105677 - transmembrane protein 147

WDR45B

Gene (Entity type)

ENSG00000141580 - WD repeat domain 45B

DEAF1

Gene (Entity type)

ENSG00000177030 - DEAF1 transcription factor

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Community

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.