GSE213588 trametinib NF1 10 v 6 human dn (Gene Set)

Dcc Asset:

rummageo chemical perturbations.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

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Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with GSE213588_trametinib_NF1_10_v_6_human_dn.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with GSE213588_trametinib_NF1_10_v_6_human_dn.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with GSE213588_trametinib_NF1_10_v_6_human_dn.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with GSE213588_trametinib_NF1_10_v_6_human_dn.

Results found

Linked to

	Label	Description
	PLOD3 Gene (Entity type)	ENSG00000106397 - procollagen-lysine,2-oxoglutarate 5-dioxygenase 3
	AGL Gene (Entity type)	ENSG00000162688 - amylo-alpha-1,6-glucosidase and 4-alpha-glucanotransferase
	CAT Gene (Entity type)	ENSG00000121691 - catalase
	EXT2 Gene (Entity type)	ENSG00000151348 - exostosin glycosyltransferase 2
	DAP Gene (Entity type)	ENSG00000112977 - death associated protein
	FURIN Gene (Entity type)	ENSG00000140564 - furin, paired basic amino acid cleaving enzyme
	SMAD4 Gene (Entity type)	ENSG00000141646 - SMAD family member 4
	HDAC5 Gene (Entity type)	ENSG00000108840 - histone deacetylase 5
	IL11 Gene (Entity type)	ENSG00000095752 - interleukin 11
	MEGF9 Gene (Entity type)	ENSG00000106780 - multiple EGF like domains 9

PLOD3

Gene (Entity type)

ENSG00000106397 - procollagen-lysine,2-oxoglutarate 5-dioxygenase 3

AGL

Gene (Entity type)

ENSG00000162688 - amylo-alpha-1,6-glucosidase and 4-alpha-glucanotransferase

CAT

Gene (Entity type)

ENSG00000121691 - catalase

EXT2

Gene (Entity type)

ENSG00000151348 - exostosin glycosyltransferase 2

DAP

Gene (Entity type)

ENSG00000112977 - death associated protein

FURIN

Gene (Entity type)

ENSG00000140564 - furin, paired basic amino acid cleaving enzyme

SMAD4

Gene (Entity type)

ENSG00000141646 - SMAD family member 4

HDAC5

Gene (Entity type)

ENSG00000108840 - histone deacetylase 5

IL11

Gene (Entity type)

ENSG00000095752 - interleukin 11

MEGF9

Gene (Entity type)

ENSG00000106780 - multiple EGF like domains 9

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.