DGUOK Down (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with DGUOK Down.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with DGUOK Down.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with DGUOK Down.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with DGUOK Down.

Results found

Linked to

	Label	Description
	GTF2H3 Gene (Entity type)	ENSG00000111358 - general transcription factor IIH subunit 3
	UROS Gene (Entity type)	ENSG00000188690 - uroporphyrinogen III synthase
	SIRT5 Gene (Entity type)	ENSG00000124523 - sirtuin 5
	TMEM254 Gene (Entity type)	ENSG00000133678 - transmembrane protein 254
	POR Gene (Entity type)	ENSG00000127948 - cytochrome p450 oxidoreductase
	BANF1 Gene (Entity type)	ENSG00000175334 - barrier to autointegration nuclear assembly factor 1
	MRPS18A Gene (Entity type)	ENSG00000096080 - mitochondrial ribosomal protein S18A
	NDUFB7 Gene (Entity type)	ENSG00000099795 - NADH:ubiquinone oxidoreductase subunit B7
	TIMM10 Gene (Entity type)	ENSG00000134809 - translocase of inner mitochondrial membrane 10
	SPDEF Gene (Entity type)	ENSG00000124664 - SAM pointed domain containing ETS transcription factor

GTF2H3

Gene (Entity type)

ENSG00000111358 - general transcription factor IIH subunit 3

UROS

Gene (Entity type)

ENSG00000188690 - uroporphyrinogen III synthase

SIRT5

Gene (Entity type)

ENSG00000124523 - sirtuin 5

TMEM254

Gene (Entity type)

ENSG00000133678 - transmembrane protein 254

POR

Gene (Entity type)

ENSG00000127948 - cytochrome p450 oxidoreductase

BANF1

Gene (Entity type)

ENSG00000175334 - barrier to autointegration nuclear assembly factor 1

MRPS18A

Gene (Entity type)

ENSG00000096080 - mitochondrial ribosomal protein S18A

NDUFB7

Gene (Entity type)

ENSG00000099795 - NADH:ubiquinone oxidoreductase subunit B7

TIMM10

Gene (Entity type)

ENSG00000134809 - translocase of inner mitochondrial membrane 10

SPDEF

Gene (Entity type)

ENSG00000124664 - SAM pointed domain containing ETS transcription factor

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.