GK2 Up (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with GK2 Up.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with GK2 Up.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with GK2 Up.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with GK2 Up.

Results found

Linked to

	Label	Description
	POLR3K Gene (Entity type)	ENSG00000161980 - RNA polymerase III subunit K
	AMZ2 Gene (Entity type)	ENSG00000196704 - archaelysin family metallopeptidase 2
	MZT2A Gene (Entity type)	ENSG00000173272 - mitotic spindle organizing protein 2A
	ALG5 Gene (Entity type)	ENSG00000120697 - ALG5 dolichyl-phosphate beta-glucosyltransferase
	C2 Gene (Entity type)	ENSG00000166278 - complement C2
	EFCAB11 Gene (Entity type)	ENSG00000140025 - EF-hand calcium binding domain 11
	SF3A2 Gene (Entity type)	ENSG00000104897 - splicing factor 3a subunit 2
	HRH1 Gene (Entity type)	ENSG00000196639 - histamine receptor H1
	MED28 Gene (Entity type)	ENSG00000118579 - mediator complex subunit 28
	METTL5 Gene (Entity type)	ENSG00000138382 - methyltransferase 5, N6-adenosine

POLR3K

Gene (Entity type)

ENSG00000161980 - RNA polymerase III subunit K

AMZ2

Gene (Entity type)

ENSG00000196704 - archaelysin family metallopeptidase 2

MZT2A

Gene (Entity type)

ENSG00000173272 - mitotic spindle organizing protein 2A

ALG5

Gene (Entity type)

ENSG00000120697 - ALG5 dolichyl-phosphate beta-glucosyltransferase

Gene (Entity type)

ENSG00000166278 - complement C2

EFCAB11

Gene (Entity type)

ENSG00000140025 - EF-hand calcium binding domain 11

SF3A2

Gene (Entity type)

ENSG00000104897 - splicing factor 3a subunit 2

HRH1

Gene (Entity type)

ENSG00000196639 - histamine receptor H1

MED28

Gene (Entity type)

ENSG00000118579 - mediator complex subunit 28

METTL5

Gene (Entity type)

ENSG00000138382 - methyltransferase 5, N6-adenosine

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.