ORC4 Up (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with ORC4 Up.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with ORC4 Up.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with ORC4 Up.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with ORC4 Up.

Results found

Linked to

	Label	Description
	TPRKB Gene (Entity type)	ENSG00000144034 - TP53RK binding protein
	HEY2 Gene (Entity type)	ENSG00000135547 - hes related family bHLH transcription factor with YRPW motif 2
	GATAD1 Gene (Entity type)	ENSG00000157259 - GATA zinc finger domain containing 1
	SLIRP Gene (Entity type)	ENSG00000119705 - SRA stem-loop interacting RNA binding protein
	MOCS2 Gene (Entity type)	ENSG00000164172 - molybdenum cofactor synthesis 2
	ADPRM Gene (Entity type)	ENSG00000170222 - ADP-ribose/CDP-alcohol diphosphatase, manganese dependent
	MRPL42 Gene (Entity type)	ENSG00000198015 - mitochondrial ribosomal protein L42
	MRPS33 Gene (Entity type)	ENSG00000090263 - mitochondrial ribosomal protein S33
	PAQR6 Gene (Entity type)	ENSG00000160781 - progestin and adipoQ receptor family member 6
	MT3 Gene (Entity type)	ENSG00000087250 - metallothionein 3

TPRKB

Gene (Entity type)

ENSG00000144034 - TP53RK binding protein

HEY2

Gene (Entity type)

ENSG00000135547 - hes related family bHLH transcription factor with YRPW motif 2

GATAD1

Gene (Entity type)

ENSG00000157259 - GATA zinc finger domain containing 1

SLIRP

Gene (Entity type)

ENSG00000119705 - SRA stem-loop interacting RNA binding protein

MOCS2

Gene (Entity type)

ENSG00000164172 - molybdenum cofactor synthesis 2

ADPRM

Gene (Entity type)

ENSG00000170222 - ADP-ribose/CDP-alcohol diphosphatase, manganese dependent

MRPL42

Gene (Entity type)

ENSG00000198015 - mitochondrial ribosomal protein L42

MRPS33

Gene (Entity type)

ENSG00000090263 - mitochondrial ribosomal protein S33

PAQR6

Gene (Entity type)

ENSG00000160781 - progestin and adipoQ receptor family member 6

MT3

Gene (Entity type)

ENSG00000087250 - metallothionein 3

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Community

Resources

@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.