GSE213588 trametinib NF1 10 v 3 human dn (Gene Set)

Dcc Asset:

rummageo chemical perturbations.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

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Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with GSE213588_trametinib_NF1_10_v_3_human_dn.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with GSE213588_trametinib_NF1_10_v_3_human_dn.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with GSE213588_trametinib_NF1_10_v_3_human_dn.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with GSE213588_trametinib_NF1_10_v_3_human_dn.

Results found

Linked to

	Label	Description
	AKR1A1 Gene (Entity type)	ENSG00000117448 - aldo-keto reductase family 1 member A1
	PLCG1 Gene (Entity type)	ENSG00000124181 - phospholipase C gamma 1
	PSMB2 Gene (Entity type)	ENSG00000126067 - proteasome 20S subunit beta 2
	MCCC1 Gene (Entity type)	ENSG00000078070 - methylcrotonyl-CoA carboxylase subunit 1
	PRPS1 Gene (Entity type)	ENSG00000147224 - phosphoribosyl pyrophosphate synthetase 1
	BLMH Gene (Entity type)	ENSG00000108578 - bleomycin hydrolase
	TGFBR1 Gene (Entity type)	ENSG00000106799 - transforming growth factor beta receptor 1
	RAD54L Gene (Entity type)	ENSG00000085999 - RAD54 like
	TOM1L2 Gene (Entity type)	ENSG00000175662 - target of myb1 like 2 membrane trafficking protein
	CTSF Gene (Entity type)	ENSG00000174080 - cathepsin F

AKR1A1

Gene (Entity type)

ENSG00000117448 - aldo-keto reductase family 1 member A1

PLCG1

Gene (Entity type)

ENSG00000124181 - phospholipase C gamma 1

PSMB2

Gene (Entity type)

ENSG00000126067 - proteasome 20S subunit beta 2

MCCC1

Gene (Entity type)

ENSG00000078070 - methylcrotonyl-CoA carboxylase subunit 1

PRPS1

Gene (Entity type)

ENSG00000147224 - phosphoribosyl pyrophosphate synthetase 1

BLMH

Gene (Entity type)

ENSG00000108578 - bleomycin hydrolase

TGFBR1

Gene (Entity type)

ENSG00000106799 - transforming growth factor beta receptor 1

RAD54L

Gene (Entity type)

ENSG00000085999 - RAD54 like

TOM1L2

Gene (Entity type)

ENSG00000175662 - target of myb1 like 2 membrane trafficking protein

CTSF

Gene (Entity type)

ENSG00000174080 - cathepsin F

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.