LTC4S Up (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with LTC4S Up.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with LTC4S Up.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with LTC4S Up.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with LTC4S Up.

Results found

Linked to

	Label	Description
	RBCK1 Gene (Entity type)	ENSG00000125826 - RANBP2-type and C3HC4-type zinc finger containing 1
	CYB5R3 Gene (Entity type)	ENSG00000100243 - cytochrome b5 reductase 3
	SPCS3 Gene (Entity type)	ENSG00000129128 - signal peptidase complex subunit 3
	SIGIRR Gene (Entity type)	ENSG00000185187 - single Ig and TIR domain containing
	AP2A2 Gene (Entity type)	ENSG00000183020 - adaptor related protein complex 2 subunit alpha 2
	P3H4 Gene (Entity type)	ENSG00000141696 - prolyl 3-hydroxylase family member 4 (inactive)
	MICAL3 Gene (Entity type)	ENSG00000243156 - microtubule associated monooxygenase, calponin and LIM domain containing 3
	MAD1L1 Gene (Entity type)	ENSG00000002822 - mitotic arrest deficient 1 like 1
	P3H1 Gene (Entity type)	ENSG00000117385 - prolyl 3-hydroxylase 1
	EIF4E2 Gene (Entity type)	ENSG00000135930 - eukaryotic translation initiation factor 4E family member 2

RBCK1

Gene (Entity type)

ENSG00000125826 - RANBP2-type and C3HC4-type zinc finger containing 1

CYB5R3

Gene (Entity type)

ENSG00000100243 - cytochrome b5 reductase 3

SPCS3

Gene (Entity type)

ENSG00000129128 - signal peptidase complex subunit 3

SIGIRR

Gene (Entity type)

ENSG00000185187 - single Ig and TIR domain containing

AP2A2

Gene (Entity type)

ENSG00000183020 - adaptor related protein complex 2 subunit alpha 2

P3H4

Gene (Entity type)

ENSG00000141696 - prolyl 3-hydroxylase family member 4 (inactive)

MICAL3

Gene (Entity type)

ENSG00000243156 - microtubule associated monooxygenase, calponin and LIM domain containing 3

MAD1L1

Gene (Entity type)

ENSG00000002822 - mitotic arrest deficient 1 like 1

P3H1

Gene (Entity type)

ENSG00000117385 - prolyl 3-hydroxylase 1

EIF4E2

Gene (Entity type)

ENSG00000135930 - eukaryotic translation initiation factor 4E family member 2

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.