GSE190178 MEK CDK8 inhibition 5 v 0 human dn (Gene Set)

Dcc Asset:

rummageo gene perturbations.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with GSE190178_MEK_CDK8 inhibition_5_v_0_human_dn.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with GSE190178_MEK_CDK8 inhibition_5_v_0_human_dn.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with GSE190178_MEK_CDK8 inhibition_5_v_0_human_dn.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with GSE190178_MEK_CDK8 inhibition_5_v_0_human_dn.

Results found

Linked to

	Label	Description
	PTPN12 Gene (Entity type)	ENSG00000127947 - protein tyrosine phosphatase non-receptor type 12
	SMAD2 Gene (Entity type)	ENSG00000175387 - SMAD family member 2
	PLOD3 Gene (Entity type)	ENSG00000106397 - procollagen-lysine,2-oxoglutarate 5-dioxygenase 3
	GALE Gene (Entity type)	ENSG00000117308 - UDP-galactose-4-epimerase
	GSK3B Gene (Entity type)	ENSG00000082701 - glycogen synthase kinase 3 beta
	CAT Gene (Entity type)	ENSG00000121691 - catalase
	EXT2 Gene (Entity type)	ENSG00000151348 - exostosin glycosyltransferase 2
	DAP Gene (Entity type)	ENSG00000112977 - death associated protein
	FURIN Gene (Entity type)	ENSG00000140564 - furin, paired basic amino acid cleaving enzyme
	GRB2 Gene (Entity type)	ENSG00000177885 - growth factor receptor bound protein 2

PTPN12

Gene (Entity type)

ENSG00000127947 - protein tyrosine phosphatase non-receptor type 12

SMAD2

Gene (Entity type)

ENSG00000175387 - SMAD family member 2

PLOD3

Gene (Entity type)

ENSG00000106397 - procollagen-lysine,2-oxoglutarate 5-dioxygenase 3

GALE

Gene (Entity type)

ENSG00000117308 - UDP-galactose-4-epimerase

GSK3B

Gene (Entity type)

ENSG00000082701 - glycogen synthase kinase 3 beta

CAT

Gene (Entity type)

ENSG00000121691 - catalase

EXT2

Gene (Entity type)

ENSG00000151348 - exostosin glycosyltransferase 2

DAP

Gene (Entity type)

ENSG00000112977 - death associated protein

FURIN

Gene (Entity type)

ENSG00000140564 - furin, paired basic amino acid cleaving enzyme

GRB2

Gene (Entity type)

ENSG00000177885 - growth factor receptor bound protein 2

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.