TDG Down (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with TDG Down.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with TDG Down.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with TDG Down.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with TDG Down.

Results found

Linked to

	Label	Description
	EIF4E Gene (Entity type)	ENSG00000151247 - eukaryotic translation initiation factor 4E
	SPCS3 Gene (Entity type)	ENSG00000129128 - signal peptidase complex subunit 3
	NXT1 Gene (Entity type)	ENSG00000132661 - nuclear transport factor 2 like export factor 1
	MRPS27 Gene (Entity type)	ENSG00000113048 - mitochondrial ribosomal protein S27
	RPA2 Gene (Entity type)	ENSG00000117748 - replication protein A2
	MRPL40 Gene (Entity type)	ENSG00000185608 - mitochondrial ribosomal protein L40
	TRAPPC4 Gene (Entity type)	ENSG00000196655 - trafficking protein particle complex subunit 4
	MAP2K5 Gene (Entity type)	ENSG00000137764 - mitogen-activated protein kinase kinase 5
	MORF4L1 Gene (Entity type)	ENSG00000185787 - mortality factor 4 like 1
	SIVA1 Gene (Entity type)	ENSG00000184990 - SIVA1 apoptosis inducing factor

EIF4E

Gene (Entity type)

ENSG00000151247 - eukaryotic translation initiation factor 4E

SPCS3

Gene (Entity type)

ENSG00000129128 - signal peptidase complex subunit 3

NXT1

Gene (Entity type)

ENSG00000132661 - nuclear transport factor 2 like export factor 1

MRPS27

Gene (Entity type)

ENSG00000113048 - mitochondrial ribosomal protein S27

RPA2

Gene (Entity type)

ENSG00000117748 - replication protein A2

MRPL40

Gene (Entity type)

ENSG00000185608 - mitochondrial ribosomal protein L40

TRAPPC4

Gene (Entity type)

ENSG00000196655 - trafficking protein particle complex subunit 4

MAP2K5

Gene (Entity type)

ENSG00000137764 - mitogen-activated protein kinase kinase 5

MORF4L1

Gene (Entity type)

ENSG00000185787 - mortality factor 4 like 1

SIVA1

Gene (Entity type)

ENSG00000184990 - SIVA1 apoptosis inducing factor

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Community

Resources

@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.