CLK4 Down (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with CLK4 Down.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with CLK4 Down.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with CLK4 Down.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with CLK4 Down.

Results found

Linked to

	Label	Description
	C2 Gene (Entity type)	ENSG00000166278 - complement C2
	UQCR11 Gene (Entity type)	ENSG00000127540 - ubiquinol-cytochrome c reductase, complex III subunit XI
	CCR5 Gene (Entity type)	ENSG00000160791 - C-C motif chemokine receptor 5
	SDHAF3 Gene (Entity type)	ENSG00000196636 - succinate dehydrogenase complex assembly factor 3
	EMILIN1 Gene (Entity type)	ENSG00000138080 - elastin microfibril interfacer 1
	NOX1 Gene (Entity type)	ENSG00000007952 - NADPH oxidase 1
	HSD17B8 Gene (Entity type)	ENSG00000204228 - hydroxysteroid 17-beta dehydrogenase 8
	TBXAS1 Gene (Entity type)	ENSG00000059377 - thromboxane A synthase 1
	ATP5MF Gene (Entity type)	ENSG00000241468 - ATP synthase membrane subunit f
	IGSF6 Gene (Entity type)	ENSG00000140749 - immunoglobulin superfamily member 6

Gene (Entity type)

ENSG00000166278 - complement C2

UQCR11

Gene (Entity type)

ENSG00000127540 - ubiquinol-cytochrome c reductase, complex III subunit XI

CCR5

Gene (Entity type)

ENSG00000160791 - C-C motif chemokine receptor 5

SDHAF3

Gene (Entity type)

ENSG00000196636 - succinate dehydrogenase complex assembly factor 3

EMILIN1

Gene (Entity type)

ENSG00000138080 - elastin microfibril interfacer 1

NOX1

Gene (Entity type)

ENSG00000007952 - NADPH oxidase 1

HSD17B8

Gene (Entity type)

ENSG00000204228 - hydroxysteroid 17-beta dehydrogenase 8

TBXAS1

Gene (Entity type)

ENSG00000059377 - thromboxane A synthase 1

ATP5MF

Gene (Entity type)

ENSG00000241468 - ATP synthase membrane subunit f

IGSF6

Gene (Entity type)

ENSG00000140749 - immunoglobulin superfamily member 6

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Community

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.