PIKFYVE Down (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with PIKFYVE Down.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with PIKFYVE Down.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with PIKFYVE Down.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with PIKFYVE Down.

Results found

Linked to

	Label	Description
	MAD1L1 Gene (Entity type)	ENSG00000002822 - mitotic arrest deficient 1 like 1
	BUD31 Gene (Entity type)	ENSG00000106245 - BUD31 spliceosome associated protein
	QRSL1 Gene (Entity type)	ENSG00000130348 - glutaminyl-tRNA amidotransferase subunit QRSL1
	BECN1 Gene (Entity type)	ENSG00000126581 - beclin 1
	PNOC Gene (Entity type)	ENSG00000168081 - prepronociceptin
	NUDC Gene (Entity type)	ENSG00000090273 - nuclear distribution C, dynein complex regulator
	TMEM140 Gene (Entity type)	ENSG00000146859 - transmembrane protein 140
	CLDN5 Gene (Entity type)	ENSG00000184113 - claudin 5
	APBB1IP Gene (Entity type)	ENSG00000077420 - amyloid beta precursor protein binding family B member 1 interacting protein
	PIK3C3 Gene (Entity type)	ENSG00000078142 - phosphatidylinositol 3-kinase catalytic subunit type 3

MAD1L1

Gene (Entity type)

ENSG00000002822 - mitotic arrest deficient 1 like 1

BUD31

Gene (Entity type)

ENSG00000106245 - BUD31 spliceosome associated protein

QRSL1

Gene (Entity type)

ENSG00000130348 - glutaminyl-tRNA amidotransferase subunit QRSL1

BECN1

Gene (Entity type)

ENSG00000126581 - beclin 1

PNOC

Gene (Entity type)

ENSG00000168081 - prepronociceptin

NUDC

Gene (Entity type)

ENSG00000090273 - nuclear distribution C, dynein complex regulator

TMEM140

Gene (Entity type)

ENSG00000146859 - transmembrane protein 140

CLDN5

Gene (Entity type)

ENSG00000184113 - claudin 5

APBB1IP

Gene (Entity type)

ENSG00000077420 - amyloid beta precursor protein binding family B member 1 interacting protein

PIK3C3

Gene (Entity type)

ENSG00000078142 - phosphatidylinositol 3-kinase catalytic subunit type 3

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Community

Resources

@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.