TCTA Down (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with TCTA Down.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with TCTA Down.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with TCTA Down.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with TCTA Down.

Results found

Linked to

	Label	Description
	HNRNPH2 Gene (Entity type)	ENSG00000126945 - heterogeneous nuclear ribonucleoprotein H2
	UBP1 Gene (Entity type)	ENSG00000153560 - upstream binding protein 1
	PRKAR2A Gene (Entity type)	ENSG00000114302 - protein kinase cAMP-dependent type II regulatory subunit alpha
	TAF5 Gene (Entity type)	ENSG00000148835 - TATA-box binding protein associated factor 5
	PPP1R12A Gene (Entity type)	ENSG00000058272 - protein phosphatase 1 regulatory subunit 12A
	VPS13A Gene (Entity type)	ENSG00000197969 - vacuolar protein sorting 13 homolog A
	SPCS3 Gene (Entity type)	ENSG00000129128 - signal peptidase complex subunit 3
	RFK Gene (Entity type)	ENSG00000135002 - riboflavin kinase
	ADCY3 Gene (Entity type)	ENSG00000138031 - adenylate cyclase 3
	COQ2 Gene (Entity type)	ENSG00000173085 - coenzyme Q2, polyprenyltransferase

HNRNPH2

Gene (Entity type)

ENSG00000126945 - heterogeneous nuclear ribonucleoprotein H2

UBP1

Gene (Entity type)

ENSG00000153560 - upstream binding protein 1

PRKAR2A

Gene (Entity type)

ENSG00000114302 - protein kinase cAMP-dependent type II regulatory subunit alpha

TAF5

Gene (Entity type)

ENSG00000148835 - TATA-box binding protein associated factor 5

PPP1R12A

Gene (Entity type)

ENSG00000058272 - protein phosphatase 1 regulatory subunit 12A

VPS13A

Gene (Entity type)

ENSG00000197969 - vacuolar protein sorting 13 homolog A

SPCS3

Gene (Entity type)

ENSG00000129128 - signal peptidase complex subunit 3

RFK

Gene (Entity type)

ENSG00000135002 - riboflavin kinase

ADCY3

Gene (Entity type)

ENSG00000138031 - adenylate cyclase 3

COQ2

Gene (Entity type)

ENSG00000173085 - coenzyme Q2, polyprenyltransferase

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.