C7 Down (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with C7 Down.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with C7 Down.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with C7 Down.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with C7 Down.

Results found

Linked to

	Label	Description
	MLH1 Gene (Entity type)	ENSG00000076242 - mutL homolog 1
	ADCY3 Gene (Entity type)	ENSG00000138031 - adenylate cyclase 3
	BMPR1A Gene (Entity type)	ENSG00000107779 - bone morphogenetic protein receptor type 1A
	EFEMP2 Gene (Entity type)	ENSG00000172638 - EGF-like fibulin extracellular matrix protein 2
	TMEM147 Gene (Entity type)	ENSG00000105677 - transmembrane protein 147
	EIF3K Gene (Entity type)	ENSG00000178982 - eukaryotic translation initiation factor 3 subunit K
	PPM1F Gene (Entity type)	ENSG00000100034 - protein phosphatase, Mg2+/Mn2+ dependent 1F
	PTOV1 Gene (Entity type)	ENSG00000104960 - PTOV1 extended AT-hook containing adaptor protein
	CHP2 Gene (Entity type)	ENSG00000166869 - calcineurin like EF-hand protein 2
	IL36G Gene (Entity type)	ENSG00000136688 - interleukin 36 gamma

MLH1

Gene (Entity type)

ENSG00000076242 - mutL homolog 1

ADCY3

Gene (Entity type)

ENSG00000138031 - adenylate cyclase 3

BMPR1A

Gene (Entity type)

ENSG00000107779 - bone morphogenetic protein receptor type 1A

EFEMP2

Gene (Entity type)

ENSG00000172638 - EGF-like fibulin extracellular matrix protein 2

TMEM147

Gene (Entity type)

ENSG00000105677 - transmembrane protein 147

EIF3K

Gene (Entity type)

ENSG00000178982 - eukaryotic translation initiation factor 3 subunit K

PPM1F

Gene (Entity type)

ENSG00000100034 - protein phosphatase, Mg2+/Mn2+ dependent 1F

PTOV1

Gene (Entity type)

ENSG00000104960 - PTOV1 extended AT-hook containing adaptor protein

CHP2

Gene (Entity type)

ENSG00000166869 - calcineurin like EF-hand protein 2

IL36G

Gene (Entity type)

ENSG00000136688 - interleukin 36 gamma

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.