SRM Down (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with SRM Down.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with SRM Down.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with SRM Down.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with SRM Down.

Results found

Linked to

	Label	Description
	PLK4 Gene (Entity type)	ENSG00000142731 - polo like kinase 4
	CA3 Gene (Entity type)	ENSG00000164879 - carbonic anhydrase 3
	SPCS3 Gene (Entity type)	ENSG00000129128 - signal peptidase complex subunit 3
	RBM8A Gene (Entity type)	ENSG00000265241 - RNA binding motif protein 8A
	RBL1 Gene (Entity type)	ENSG00000080839 - RB transcriptional corepressor like 1
	UGT2A3 Gene (Entity type)	ENSG00000135220 - UDP glucuronosyltransferase family 2 member A3
	KLHL2 Gene (Entity type)	ENSG00000109466 - kelch like family member 2
	MIA3 Gene (Entity type)	ENSG00000154305 - MIA SH3 domain ER export factor 3
	GCG Gene (Entity type)	ENSG00000115263 - glucagon
	IL20RA Gene (Entity type)	ENSG00000016402 - interleukin 20 receptor subunit alpha

PLK4

Gene (Entity type)

ENSG00000142731 - polo like kinase 4

CA3

Gene (Entity type)

ENSG00000164879 - carbonic anhydrase 3

SPCS3

Gene (Entity type)

ENSG00000129128 - signal peptidase complex subunit 3

RBM8A

Gene (Entity type)

ENSG00000265241 - RNA binding motif protein 8A

RBL1

Gene (Entity type)

ENSG00000080839 - RB transcriptional corepressor like 1

UGT2A3

Gene (Entity type)

ENSG00000135220 - UDP glucuronosyltransferase family 2 member A3

KLHL2

Gene (Entity type)

ENSG00000109466 - kelch like family member 2

MIA3

Gene (Entity type)

ENSG00000154305 - MIA SH3 domain ER export factor 3

GCG

Gene (Entity type)

ENSG00000115263 - glucagon

IL20RA

Gene (Entity type)

ENSG00000016402 - interleukin 20 receptor subunit alpha

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CFDE Workbench

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Community

Resources

@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.