GSE246325 PRMT5 inhibition 0 v 5 human up (Gene Set)

Dcc Asset:

rummageo gene perturbations.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with GSE246325_PRMT5 inhibition_0_v_5_human_up.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with GSE246325_PRMT5 inhibition_0_v_5_human_up.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with GSE246325_PRMT5 inhibition_0_v_5_human_up.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with GSE246325_PRMT5 inhibition_0_v_5_human_up.

Results found

Linked to

	Label	Description
	BRAF Gene (Entity type)	ENSG00000157764 - B-Raf proto-oncogene, serine/threonine kinase
	CSNK2A2 Gene (Entity type)	ENSG00000070770 - casein kinase 2 alpha 2
	AGL Gene (Entity type)	ENSG00000162688 - amylo-alpha-1,6-glucosidase and 4-alpha-glucanotransferase
	PLCG1 Gene (Entity type)	ENSG00000124181 - phospholipase C gamma 1
	ROCK2 Gene (Entity type)	ENSG00000134318 - Rho associated coiled-coil containing protein kinase 2
	EGLN1 Gene (Entity type)	ENSG00000135766 - egl-9 family hypoxia inducible factor 1
	PPP1CC Gene (Entity type)	ENSG00000186298 - protein phosphatase 1 catalytic subunit gamma
	CCNC Gene (Entity type)	ENSG00000112237 - cyclin C
	OGFOD1 Gene (Entity type)	ENSG00000087263 - 2-oxoglutarate and iron dependent oxygenase domain containing 1
	SIK3 Gene (Entity type)	ENSG00000160584 - SIK family kinase 3

BRAF

Gene (Entity type)

ENSG00000157764 - B-Raf proto-oncogene, serine/threonine kinase

CSNK2A2

Gene (Entity type)

ENSG00000070770 - casein kinase 2 alpha 2

AGL

Gene (Entity type)

ENSG00000162688 - amylo-alpha-1,6-glucosidase and 4-alpha-glucanotransferase

PLCG1

Gene (Entity type)

ENSG00000124181 - phospholipase C gamma 1

ROCK2

Gene (Entity type)

ENSG00000134318 - Rho associated coiled-coil containing protein kinase 2

EGLN1

Gene (Entity type)

ENSG00000135766 - egl-9 family hypoxia inducible factor 1

PPP1CC

Gene (Entity type)

ENSG00000186298 - protein phosphatase 1 catalytic subunit gamma

CCNC

Gene (Entity type)

ENSG00000112237 - cyclin C

OGFOD1

Gene (Entity type)

ENSG00000087263 - 2-oxoglutarate and iron dependent oxygenase domain containing 1

SIK3

Gene (Entity type)

ENSG00000160584 - SIK family kinase 3

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.