GSE248770 STIM1 knockout Hep 3B2.1-7 Sorafenib 0 v 1 human up (Gene Set)

Dcc Asset:

rummageo gene perturbations.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

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Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with GSE248770_STIM1 knockout_Hep 3B2.1-7_Sorafenib_0_v_1_human_up.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with GSE248770_STIM1 knockout_Hep 3B2.1-7_Sorafenib_0_v_1_human_up.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with GSE248770_STIM1 knockout_Hep 3B2.1-7_Sorafenib_0_v_1_human_up.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with GSE248770_STIM1 knockout_Hep 3B2.1-7_Sorafenib_0_v_1_human_up.

Results found

Linked to

	Label	Description
	SMAD2 Gene (Entity type)	ENSG00000175387 - SMAD family member 2
	PIK3CB Gene (Entity type)	ENSG00000051382 - phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
	BRAF Gene (Entity type)	ENSG00000157764 - B-Raf proto-oncogene, serine/threonine kinase
	PPP2R2C Gene (Entity type)	ENSG00000074211 - protein phosphatase 2 regulatory subunit Bgamma
	GSK3B Gene (Entity type)	ENSG00000082701 - glycogen synthase kinase 3 beta
	AGL Gene (Entity type)	ENSG00000162688 - amylo-alpha-1,6-glucosidase and 4-alpha-glucanotransferase
	MLH1 Gene (Entity type)	ENSG00000076242 - mutL homolog 1
	RFK Gene (Entity type)	ENSG00000135002 - riboflavin kinase
	ROCK2 Gene (Entity type)	ENSG00000134318 - Rho associated coiled-coil containing protein kinase 2
	SMAD4 Gene (Entity type)	ENSG00000141646 - SMAD family member 4

SMAD2

Gene (Entity type)

ENSG00000175387 - SMAD family member 2

PIK3CB

Gene (Entity type)

ENSG00000051382 - phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta

BRAF

Gene (Entity type)

ENSG00000157764 - B-Raf proto-oncogene, serine/threonine kinase

PPP2R2C

Gene (Entity type)

ENSG00000074211 - protein phosphatase 2 regulatory subunit Bgamma

GSK3B

Gene (Entity type)

ENSG00000082701 - glycogen synthase kinase 3 beta

AGL

Gene (Entity type)

ENSG00000162688 - amylo-alpha-1,6-glucosidase and 4-alpha-glucanotransferase

MLH1

Gene (Entity type)

ENSG00000076242 - mutL homolog 1

RFK

Gene (Entity type)

ENSG00000135002 - riboflavin kinase

ROCK2

Gene (Entity type)

ENSG00000134318 - Rho associated coiled-coil containing protein kinase 2

SMAD4

Gene (Entity type)

ENSG00000141646 - SMAD family member 4

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.