HES1 Down (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with HES1 Down.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with HES1 Down.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with HES1 Down.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with HES1 Down.

Results found

Linked to

	Label	Description
	SMAD2 Gene (Entity type)	ENSG00000175387 - SMAD family member 2
	ASMTL Gene (Entity type)	ENSG00000169093 - acetylserotonin O-methyltransferase like
	ASMTL Gene (Entity type)	ENSG00000292339 - acetylserotonin O-methyltransferase like
	RAP1GDS1 Gene (Entity type)	ENSG00000138698 - Rap1 GTPase-GDP dissociation stimulator 1
	NOX1 Gene (Entity type)	ENSG00000007952 - NADPH oxidase 1
	MICAL3 Gene (Entity type)	ENSG00000243156 - microtubule associated monooxygenase, calponin and LIM domain containing 3
	TNKS Gene (Entity type)	ENSG00000173273 - tankyrase
	CR2 Gene (Entity type)	ENSG00000117322 - complement C3d receptor 2
	ME3 Gene (Entity type)	ENSG00000151376 - malic enzyme 3
	IP6K2 Gene (Entity type)	ENSG00000068745 - inositol hexakisphosphate kinase 2

SMAD2

Gene (Entity type)

ENSG00000175387 - SMAD family member 2

ASMTL

Gene (Entity type)

ENSG00000169093 - acetylserotonin O-methyltransferase like

ASMTL

Gene (Entity type)

ENSG00000292339 - acetylserotonin O-methyltransferase like

RAP1GDS1

Gene (Entity type)

ENSG00000138698 - Rap1 GTPase-GDP dissociation stimulator 1

NOX1

Gene (Entity type)

ENSG00000007952 - NADPH oxidase 1

MICAL3

Gene (Entity type)

ENSG00000243156 - microtubule associated monooxygenase, calponin and LIM domain containing 3

TNKS

Gene (Entity type)

ENSG00000173273 - tankyrase

CR2

Gene (Entity type)

ENSG00000117322 - complement C3d receptor 2

ME3

Gene (Entity type)

ENSG00000151376 - malic enzyme 3

IP6K2

Gene (Entity type)

ENSG00000068745 - inositol hexakisphosphate kinase 2

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Community

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.