POLE2 Down (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with POLE2 Down.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with POLE2 Down.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with POLE2 Down.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with POLE2 Down.

Results found

Linked to

	Label	Description
	ARF6 Gene (Entity type)	ENSG00000165527 - ARF GTPase 6
	MED1 Gene (Entity type)	ENSG00000125686 - mediator complex subunit 1
	DCAF10 Gene (Entity type)	ENSG00000122741 - DDB1 and CUL4 associated factor 10
	ARPP21 Gene (Entity type)	ENSG00000172995 - cAMP regulated phosphoprotein 21
	PSMA3 Gene (Entity type)	ENSG00000100567 - proteasome 20S subunit alpha 3
	RRP15 Gene (Entity type)	ENSG00000067533 - ribosomal RNA processing 15 homolog
	MRPL42 Gene (Entity type)	ENSG00000198015 - mitochondrial ribosomal protein L42
	BCCIP Gene (Entity type)	ENSG00000107949 - BRCA2 and CDKN1A interacting protein
	TMEM168 Gene (Entity type)	ENSG00000146802 - transmembrane protein 168
	USP15 Gene (Entity type)	ENSG00000135655 - ubiquitin specific peptidase 15

ARF6

Gene (Entity type)

ENSG00000165527 - ARF GTPase 6

MED1

Gene (Entity type)

ENSG00000125686 - mediator complex subunit 1

DCAF10

Gene (Entity type)

ENSG00000122741 - DDB1 and CUL4 associated factor 10

ARPP21

Gene (Entity type)

ENSG00000172995 - cAMP regulated phosphoprotein 21

PSMA3

Gene (Entity type)

ENSG00000100567 - proteasome 20S subunit alpha 3

RRP15

Gene (Entity type)

ENSG00000067533 - ribosomal RNA processing 15 homolog

MRPL42

Gene (Entity type)

ENSG00000198015 - mitochondrial ribosomal protein L42

BCCIP

Gene (Entity type)

ENSG00000107949 - BRCA2 and CDKN1A interacting protein

TMEM168

Gene (Entity type)

ENSG00000146802 - transmembrane protein 168

USP15

Gene (Entity type)

ENSG00000135655 - ubiquitin specific peptidase 15

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Community

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.