MRTO4 Down (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with MRTO4 Down.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with MRTO4 Down.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with MRTO4 Down.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with MRTO4 Down.

Results found

Linked to

	Label	Description
	POLR3K Gene (Entity type)	ENSG00000161980 - RNA polymerase III subunit K
	CAD Gene (Entity type)	ENSG00000084774 - carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
	DICER1 Gene (Entity type)	ENSG00000100697 - dicer 1, ribonuclease III
	GABARAPL2 Gene (Entity type)	ENSG00000034713 - GABA type A receptor associated protein like 2
	MLC1 Gene (Entity type)	ENSG00000100427 - modulator of VRAC current 1
	VIPR1 Gene (Entity type)	ENSG00000114812 - vasoactive intestinal peptide receptor 1
	MGRN1 Gene (Entity type)	ENSG00000102858 - mahogunin ring finger 1
	CBFA2T3 Gene (Entity type)	ENSG00000129993 - CBFA2/RUNX1 partner transcriptional co-repressor 3
	SKI Gene (Entity type)	ENSG00000157933 - SKI proto-oncogene
	MAN1A2 Gene (Entity type)	ENSG00000198162 - mannosidase alpha class 1A member 2

POLR3K

Gene (Entity type)

ENSG00000161980 - RNA polymerase III subunit K

CAD

Gene (Entity type)

ENSG00000084774 - carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase

DICER1

Gene (Entity type)

ENSG00000100697 - dicer 1, ribonuclease III

GABARAPL2

Gene (Entity type)

ENSG00000034713 - GABA type A receptor associated protein like 2

MLC1

Gene (Entity type)

ENSG00000100427 - modulator of VRAC current 1

VIPR1

Gene (Entity type)

ENSG00000114812 - vasoactive intestinal peptide receptor 1

MGRN1

Gene (Entity type)

ENSG00000102858 - mahogunin ring finger 1

CBFA2T3

Gene (Entity type)

ENSG00000129993 - CBFA2/RUNX1 partner transcriptional co-repressor 3

SKI

Gene (Entity type)

ENSG00000157933 - SKI proto-oncogene

MAN1A2

Gene (Entity type)

ENSG00000198162 - mannosidase alpha class 1A member 2

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.