GSE190178 MEK CDK8 inhibition 3 v 2 human dn (Gene Set)

Dcc Asset:

rummageo gene perturbations.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with GSE190178_MEK_CDK8 inhibition_3_v_2_human_dn.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with GSE190178_MEK_CDK8 inhibition_3_v_2_human_dn.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with GSE190178_MEK_CDK8 inhibition_3_v_2_human_dn.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with GSE190178_MEK_CDK8 inhibition_3_v_2_human_dn.

Results found

Linked to

	Label	Description
	PGRMC1 Gene (Entity type)	ENSG00000101856 - progesterone receptor membrane component 1
	HDAC2 Gene (Entity type)	ENSG00000196591 - histone deacetylase 2
	RPS6 Gene (Entity type)	ENSG00000137154 - ribosomal protein S6
	CPNE3 Gene (Entity type)	ENSG00000085719 - copine 3
	GSK3B Gene (Entity type)	ENSG00000082701 - glycogen synthase kinase 3 beta
	ACADM Gene (Entity type)	ENSG00000117054 - acyl-CoA dehydrogenase medium chain
	NRAS Gene (Entity type)	ENSG00000213281 - NRAS proto-oncogene, GTPase
	AGL Gene (Entity type)	ENSG00000162688 - amylo-alpha-1,6-glucosidase and 4-alpha-glucanotransferase
	RFK Gene (Entity type)	ENSG00000135002 - riboflavin kinase
	HDAC5 Gene (Entity type)	ENSG00000108840 - histone deacetylase 5

PGRMC1

Gene (Entity type)

ENSG00000101856 - progesterone receptor membrane component 1

HDAC2

Gene (Entity type)

ENSG00000196591 - histone deacetylase 2

RPS6

Gene (Entity type)

ENSG00000137154 - ribosomal protein S6

CPNE3

Gene (Entity type)

ENSG00000085719 - copine 3

GSK3B

Gene (Entity type)

ENSG00000082701 - glycogen synthase kinase 3 beta

ACADM

Gene (Entity type)

ENSG00000117054 - acyl-CoA dehydrogenase medium chain

NRAS

Gene (Entity type)

ENSG00000213281 - NRAS proto-oncogene, GTPase

AGL

Gene (Entity type)

ENSG00000162688 - amylo-alpha-1,6-glucosidase and 4-alpha-glucanotransferase

RFK

Gene (Entity type)

ENSG00000135002 - riboflavin kinase

HDAC5

Gene (Entity type)

ENSG00000108840 - histone deacetylase 5

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.