CHKA Down (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with CHKA Down.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with CHKA Down.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with CHKA Down.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with CHKA Down.

Results found

Linked to

	Label	Description
	COQ2 Gene (Entity type)	ENSG00000173085 - coenzyme Q2, polyprenyltransferase
	PLK4 Gene (Entity type)	ENSG00000142731 - polo like kinase 4
	PIGB Gene (Entity type)	ENSG00000069943 - phosphatidylinositol glycan anchor biosynthesis class B
	NFIC Gene (Entity type)	ENSG00000141905 - nuclear factor I C
	POLD2 Gene (Entity type)	ENSG00000106628 - DNA polymerase delta 2, accessory subunit
	TMPRSS11E Gene (Entity type)	ENSG00000087128 - transmembrane serine protease 11E
	ANKS1A Gene (Entity type)	ENSG00000064999 - ankyrin repeat and sterile alpha motif domain containing 1A
	YEATS4 Gene (Entity type)	ENSG00000127337 - YEATS domain containing 4
	GCG Gene (Entity type)	ENSG00000115263 - glucagon
	MPHOSPH9 Gene (Entity type)	ENSG00000051825 - M-phase phosphoprotein 9

COQ2

Gene (Entity type)

ENSG00000173085 - coenzyme Q2, polyprenyltransferase

PLK4

Gene (Entity type)

ENSG00000142731 - polo like kinase 4

PIGB

Gene (Entity type)

ENSG00000069943 - phosphatidylinositol glycan anchor biosynthesis class B

NFIC

Gene (Entity type)

ENSG00000141905 - nuclear factor I C

POLD2

Gene (Entity type)

ENSG00000106628 - DNA polymerase delta 2, accessory subunit

TMPRSS11E

Gene (Entity type)

ENSG00000087128 - transmembrane serine protease 11E

ANKS1A

Gene (Entity type)

ENSG00000064999 - ankyrin repeat and sterile alpha motif domain containing 1A

YEATS4

Gene (Entity type)

ENSG00000127337 - YEATS domain containing 4

GCG

Gene (Entity type)

ENSG00000115263 - glucagon

MPHOSPH9

Gene (Entity type)

ENSG00000051825 - M-phase phosphoprotein 9

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Community

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.