POLB Down (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with POLB Down.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with POLB Down.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with POLB Down.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with POLB Down.

Results found

Linked to

	Label	Description
	GTF2H3 Gene (Entity type)	ENSG00000111358 - general transcription factor IIH subunit 3
	PFDN2 Gene (Entity type)	ENSG00000143256 - prefoldin subunit 2
	IL11 Gene (Entity type)	ENSG00000095752 - interleukin 11
	CASD1 Gene (Entity type)	ENSG00000127995 - CAS1 domain sialic acid O acetyltransferase 1
	CASP9 Gene (Entity type)	ENSG00000132906 - caspase 9
	DDX27 Gene (Entity type)	ENSG00000124228 - DEAD-box helicase 27
	DVL3 Gene (Entity type)	ENSG00000161202 - dishevelled segment polarity protein 3
	UBAP2 Gene (Entity type)	ENSG00000137073 - ubiquitin associated protein 2
	SV2B Gene (Entity type)	ENSG00000185518 - synaptic vesicle glycoprotein 2B
	CSNK2A1 Gene (Entity type)	ENSG00000101266 - casein kinase 2 alpha 1

GTF2H3

Gene (Entity type)

ENSG00000111358 - general transcription factor IIH subunit 3

PFDN2

Gene (Entity type)

ENSG00000143256 - prefoldin subunit 2

IL11

Gene (Entity type)

ENSG00000095752 - interleukin 11

CASD1

Gene (Entity type)

ENSG00000127995 - CAS1 domain sialic acid O acetyltransferase 1

CASP9

Gene (Entity type)

ENSG00000132906 - caspase 9

DDX27

Gene (Entity type)

ENSG00000124228 - DEAD-box helicase 27

DVL3

Gene (Entity type)

ENSG00000161202 - dishevelled segment polarity protein 3

UBAP2

Gene (Entity type)

ENSG00000137073 - ubiquitin associated protein 2

SV2B

Gene (Entity type)

ENSG00000185518 - synaptic vesicle glycoprotein 2B

CSNK2A1

Gene (Entity type)

ENSG00000101266 - casein kinase 2 alpha 1

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Community

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.