PAK4 Up (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with PAK4 Up.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with PAK4 Up.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with PAK4 Up.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with PAK4 Up.

Results found

Linked to

	Label	Description
	CTNS Gene (Entity type)	ENSG00000040531 - cystinosin, lysosomal cystine transporter
	HEY2 Gene (Entity type)	ENSG00000135547 - hes related family bHLH transcription factor with YRPW motif 2
	STYXL1 Gene (Entity type)	ENSG00000127952 - serine/threonine/tyrosine interacting like 1
	TNFRSF25 Gene (Entity type)	ENSG00000215788 - TNF receptor superfamily member 25
	TRAPPC6A Gene (Entity type)	ENSG00000007255 - trafficking protein particle complex subunit 6A
	PLCH1 Gene (Entity type)	ENSG00000114805 - phospholipase C eta 1
	PAAF1 Gene (Entity type)	ENSG00000175575 - proteasomal ATPase associated factor 1
	SPG11 Gene (Entity type)	ENSG00000104133 - SPG11 vesicle trafficking associated, spatacsin
	VPREB1 Gene (Entity type)	ENSG00000169575 - V-set pre-B cell surrogate light chain 1
	CBR4 Gene (Entity type)	ENSG00000145439 - carbonyl reductase 4

CTNS

Gene (Entity type)

ENSG00000040531 - cystinosin, lysosomal cystine transporter

HEY2

Gene (Entity type)

ENSG00000135547 - hes related family bHLH transcription factor with YRPW motif 2

STYXL1

Gene (Entity type)

ENSG00000127952 - serine/threonine/tyrosine interacting like 1

TNFRSF25

Gene (Entity type)

ENSG00000215788 - TNF receptor superfamily member 25

TRAPPC6A

Gene (Entity type)

ENSG00000007255 - trafficking protein particle complex subunit 6A

PLCH1

Gene (Entity type)

ENSG00000114805 - phospholipase C eta 1

PAAF1

Gene (Entity type)

ENSG00000175575 - proteasomal ATPase associated factor 1

SPG11

Gene (Entity type)

ENSG00000104133 - SPG11 vesicle trafficking associated, spatacsin

VPREB1

Gene (Entity type)

ENSG00000169575 - V-set pre-B cell surrogate light chain 1

CBR4

Gene (Entity type)

ENSG00000145439 - carbonyl reductase 4

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CFDE Workbench

Consortium

Community

Resources

@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.