MTTP Down (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with MTTP Down.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with MTTP Down.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with MTTP Down.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with MTTP Down.

Results found

Linked to

	Label	Description
	AKR1A1 Gene (Entity type)	ENSG00000117448 - aldo-keto reductase family 1 member A1
	PRPS1 Gene (Entity type)	ENSG00000147224 - phosphoribosyl pyrophosphate synthetase 1
	PAFAH1B3 Gene (Entity type)	ENSG00000079462 - platelet activating factor acetylhydrolase 1b catalytic subunit 3
	RUVBL2 Gene (Entity type)	ENSG00000183207 - RuvB like AAA ATPase 2
	IGSF1 Gene (Entity type)	ENSG00000147255 - immunoglobulin superfamily member 1
	GNG7 Gene (Entity type)	ENSG00000176533 - G protein subunit gamma 7
	KIF1C Gene (Entity type)	ENSG00000129250 - kinesin family member 1C
	WWOX Gene (Entity type)	ENSG00000186153 - WW domain containing oxidoreductase
	TICAM1 Gene (Entity type)	ENSG00000127666 - TIR domain containing adaptor molecule 1
	SIVA1 Gene (Entity type)	ENSG00000184990 - SIVA1 apoptosis inducing factor

AKR1A1

Gene (Entity type)

ENSG00000117448 - aldo-keto reductase family 1 member A1

PRPS1

Gene (Entity type)

ENSG00000147224 - phosphoribosyl pyrophosphate synthetase 1

PAFAH1B3

Gene (Entity type)

ENSG00000079462 - platelet activating factor acetylhydrolase 1b catalytic subunit 3

RUVBL2

Gene (Entity type)

ENSG00000183207 - RuvB like AAA ATPase 2

IGSF1

Gene (Entity type)

ENSG00000147255 - immunoglobulin superfamily member 1

GNG7

Gene (Entity type)

ENSG00000176533 - G protein subunit gamma 7

KIF1C

Gene (Entity type)

ENSG00000129250 - kinesin family member 1C

WWOX

Gene (Entity type)

ENSG00000186153 - WW domain containing oxidoreductase

TICAM1

Gene (Entity type)

ENSG00000127666 - TIR domain containing adaptor molecule 1

SIVA1

Gene (Entity type)

ENSG00000184990 - SIVA1 apoptosis inducing factor

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CFDE Workbench

Consortium

Community

Resources

@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.