GSE222676 ABCA1 knockout IMR-90 1 v 0 human up (Gene Set)

Dcc Asset:

rummageo gene perturbations.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

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Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with GSE222676_ABCA1 knockout_IMR-90_1_v_0_human_up.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with GSE222676_ABCA1 knockout_IMR-90_1_v_0_human_up.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with GSE222676_ABCA1 knockout_IMR-90_1_v_0_human_up.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with GSE222676_ABCA1 knockout_IMR-90_1_v_0_human_up.

Results found

Linked to

	Label	Description
	CAT Gene (Entity type)	ENSG00000121691 - catalase
	RBCK1 Gene (Entity type)	ENSG00000125826 - RANBP2-type and C3HC4-type zinc finger containing 1
	IL10RB Gene (Entity type)	ENSG00000243646 - interleukin 10 receptor subunit beta
	DTX3L Gene (Entity type)	ENSG00000163840 - deltex E3 ubiquitin ligase 3L
	NRG1 Gene (Entity type)	ENSG00000157168 - neuregulin 1
	HLA-DMA Gene (Entity type)	ENSG00000204257 - major histocompatibility complex, class II, DM alpha
	ULK1 Gene (Entity type)	ENSG00000177169 - unc-51 like autophagy activating kinase 1
	ADAM15 Gene (Entity type)	ENSG00000143537 - ADAM metallopeptidase domain 15
	PSEN1 Gene (Entity type)	ENSG00000080815 - presenilin 1
	NRBF2 Gene (Entity type)	ENSG00000148572 - nuclear receptor binding factor 2

CAT

Gene (Entity type)

ENSG00000121691 - catalase

RBCK1

Gene (Entity type)

ENSG00000125826 - RANBP2-type and C3HC4-type zinc finger containing 1

IL10RB

Gene (Entity type)

ENSG00000243646 - interleukin 10 receptor subunit beta

DTX3L

Gene (Entity type)

ENSG00000163840 - deltex E3 ubiquitin ligase 3L

NRG1

Gene (Entity type)

ENSG00000157168 - neuregulin 1

HLA-DMA

Gene (Entity type)

ENSG00000204257 - major histocompatibility complex, class II, DM alpha

ULK1

Gene (Entity type)

ENSG00000177169 - unc-51 like autophagy activating kinase 1

ADAM15

Gene (Entity type)

ENSG00000143537 - ADAM metallopeptidase domain 15

PSEN1

Gene (Entity type)

ENSG00000080815 - presenilin 1

NRBF2

Gene (Entity type)

ENSG00000148572 - nuclear receptor binding factor 2

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.