COBL Down (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with COBL Down.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with COBL Down.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with COBL Down.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with COBL Down.

Results found

Linked to

	Label	Description
	DUSP11 Gene (Entity type)	ENSG00000144048 - dual specificity phosphatase 11
	PPP2R2B Gene (Entity type)	ENSG00000156475 - protein phosphatase 2 regulatory subunit Bbeta
	VPS4B Gene (Entity type)	ENSG00000119541 - vacuolar protein sorting 4 homolog B
	UGT2A3 Gene (Entity type)	ENSG00000135220 - UDP glucuronosyltransferase family 2 member A3
	PREPL Gene (Entity type)	ENSG00000138078 - prolyl endopeptidase like
	HIGD2A Gene (Entity type)	ENSG00000146066 - HIG1 hypoxia inducible domain family member 2A
	MAP2 Gene (Entity type)	ENSG00000078018 - microtubule associated protein 2
	RAB8B Gene (Entity type)	ENSG00000166128 - RAB8B, member RAS oncogene family
	SS18 Gene (Entity type)	ENSG00000141380 - SS18 subunit of BAF chromatin remodeling complex
	VPREB1 Gene (Entity type)	ENSG00000169575 - V-set pre-B cell surrogate light chain 1

DUSP11

Gene (Entity type)

ENSG00000144048 - dual specificity phosphatase 11

PPP2R2B

Gene (Entity type)

ENSG00000156475 - protein phosphatase 2 regulatory subunit Bbeta

VPS4B

Gene (Entity type)

ENSG00000119541 - vacuolar protein sorting 4 homolog B

UGT2A3

Gene (Entity type)

ENSG00000135220 - UDP glucuronosyltransferase family 2 member A3

PREPL

Gene (Entity type)

ENSG00000138078 - prolyl endopeptidase like

HIGD2A

Gene (Entity type)

ENSG00000146066 - HIG1 hypoxia inducible domain family member 2A

MAP2

Gene (Entity type)

ENSG00000078018 - microtubule associated protein 2

RAB8B

Gene (Entity type)

ENSG00000166128 - RAB8B, member RAS oncogene family

SS18

Gene (Entity type)

ENSG00000141380 - SS18 subunit of BAF chromatin remodeling complex

VPREB1

Gene (Entity type)

ENSG00000169575 - V-set pre-B cell surrogate light chain 1

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CFDE Workbench

Consortium

Community

Resources

@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.