GSE185872 methotrexate macrophage 0 v 2 human up (Gene Set)

Dcc Asset:

rummageo chemical perturbations.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with GSE185872_methotrexate_macrophage_0_v_2_human_up.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with GSE185872_methotrexate_macrophage_0_v_2_human_up.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with GSE185872_methotrexate_macrophage_0_v_2_human_up.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with GSE185872_methotrexate_macrophage_0_v_2_human_up.

Results found

Linked to

	Label	Description
	CCNC Gene (Entity type)	ENSG00000112237 - cyclin C
	PPM1D Gene (Entity type)	ENSG00000170836 - protein phosphatase, Mg2+/Mn2+ dependent 1D
	KCNK5 Gene (Entity type)	ENSG00000164626 - potassium two pore domain channel subfamily K member 5
	BBC3 Gene (Entity type)	ENSG00000105327 - BCL2 binding component 3
	ADGRB2 Gene (Entity type)	ENSG00000121753 - adhesion G protein-coupled receptor B2
	RRM2B Gene (Entity type)	ENSG00000048392 - ribonucleotide reductase regulatory TP53 inducible subunit M2B
	SRMS Gene (Entity type)	ENSG00000125508 - src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites
	MCOLN2 Gene (Entity type)	ENSG00000153898 - mucolipin TRP cation channel 2
	UBD Gene (Entity type)	ENSG00000213886 - ubiquitin like modifier D
	VWCE Gene (Entity type)	ENSG00000167992 - von Willebrand factor C and EGF domains

CCNC

Gene (Entity type)

ENSG00000112237 - cyclin C

PPM1D

Gene (Entity type)

ENSG00000170836 - protein phosphatase, Mg2+/Mn2+ dependent 1D

KCNK5

Gene (Entity type)

ENSG00000164626 - potassium two pore domain channel subfamily K member 5

BBC3

Gene (Entity type)

ENSG00000105327 - BCL2 binding component 3

ADGRB2

Gene (Entity type)

ENSG00000121753 - adhesion G protein-coupled receptor B2

RRM2B

Gene (Entity type)

ENSG00000048392 - ribonucleotide reductase regulatory TP53 inducible subunit M2B

SRMS

Gene (Entity type)

ENSG00000125508 - src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites

MCOLN2

Gene (Entity type)

ENSG00000153898 - mucolipin TRP cation channel 2

UBD

Gene (Entity type)

ENSG00000213886 - ubiquitin like modifier D

VWCE

Gene (Entity type)

ENSG00000167992 - von Willebrand factor C and EGF domains

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.