NPC1 Down (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with NPC1 Down.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with NPC1 Down.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with NPC1 Down.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with NPC1 Down.

Results found

Linked to

	Label	Description
	SMAD2 Gene (Entity type)	ENSG00000175387 - SMAD family member 2
	GNG7 Gene (Entity type)	ENSG00000176533 - G protein subunit gamma 7
	SERPINA6 Gene (Entity type)	ENSG00000170099 - serpin family A member 6
	ZDHHC4 Gene (Entity type)	ENSG00000136247 - zDHHC palmitoyltransferase 4
	TFCP2L1 Gene (Entity type)	ENSG00000115112 - transcription factor CP2 like 1
	RPL26L1 Gene (Entity type)	ENSG00000037241 - ribosomal protein L26 like 1
	MZT2A Gene (Entity type)	ENSG00000173272 - mitotic spindle organizing protein 2A
	SS18 Gene (Entity type)	ENSG00000141380 - SS18 subunit of BAF chromatin remodeling complex
	VPREB1 Gene (Entity type)	ENSG00000169575 - V-set pre-B cell surrogate light chain 1
	EIF6 Gene (Entity type)	ENSG00000242372 - eukaryotic translation initiation factor 6

SMAD2

Gene (Entity type)

ENSG00000175387 - SMAD family member 2

GNG7

Gene (Entity type)

ENSG00000176533 - G protein subunit gamma 7

SERPINA6

Gene (Entity type)

ENSG00000170099 - serpin family A member 6

ZDHHC4

Gene (Entity type)

ENSG00000136247 - zDHHC palmitoyltransferase 4

TFCP2L1

Gene (Entity type)

ENSG00000115112 - transcription factor CP2 like 1

RPL26L1

Gene (Entity type)

ENSG00000037241 - ribosomal protein L26 like 1

MZT2A

Gene (Entity type)

ENSG00000173272 - mitotic spindle organizing protein 2A

SS18

Gene (Entity type)

ENSG00000141380 - SS18 subunit of BAF chromatin remodeling complex

VPREB1

Gene (Entity type)

ENSG00000169575 - V-set pre-B cell surrogate light chain 1

EIF6

Gene (Entity type)

ENSG00000242372 - eukaryotic translation initiation factor 6

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.