GSE221577 PIK3R1 knockout 1 v 5 human up (Gene Set)

Dcc Asset:

rummageo gene perturbations.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with GSE221577_PIK3R1 knockout_1_v_5_human_up.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with GSE221577_PIK3R1 knockout_1_v_5_human_up.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with GSE221577_PIK3R1 knockout_1_v_5_human_up.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with GSE221577_PIK3R1 knockout_1_v_5_human_up.

Results found

Linked to

	Label	Description
	KDM5A Gene (Entity type)	ENSG00000073614 - lysine demethylase 5A
	ACADM Gene (Entity type)	ENSG00000117054 - acyl-CoA dehydrogenase medium chain
	MLH1 Gene (Entity type)	ENSG00000076242 - mutL homolog 1
	PSMB2 Gene (Entity type)	ENSG00000126067 - proteasome 20S subunit beta 2
	ERN1 Gene (Entity type)	ENSG00000178607 - endoplasmic reticulum to nucleus signaling 1
	MCCC1 Gene (Entity type)	ENSG00000078070 - methylcrotonyl-CoA carboxylase subunit 1
	PRPS1 Gene (Entity type)	ENSG00000147224 - phosphoribosyl pyrophosphate synthetase 1
	ADAM15 Gene (Entity type)	ENSG00000143537 - ADAM metallopeptidase domain 15
	MMRN1 Gene (Entity type)	ENSG00000138722 - multimerin 1
	PRCP Gene (Entity type)	ENSG00000137509 - prolylcarboxypeptidase

KDM5A

Gene (Entity type)

ENSG00000073614 - lysine demethylase 5A

ACADM

Gene (Entity type)

ENSG00000117054 - acyl-CoA dehydrogenase medium chain

MLH1

Gene (Entity type)

ENSG00000076242 - mutL homolog 1

PSMB2

Gene (Entity type)

ENSG00000126067 - proteasome 20S subunit beta 2

ERN1

Gene (Entity type)

ENSG00000178607 - endoplasmic reticulum to nucleus signaling 1

MCCC1

Gene (Entity type)

ENSG00000078070 - methylcrotonyl-CoA carboxylase subunit 1

PRPS1

Gene (Entity type)

ENSG00000147224 - phosphoribosyl pyrophosphate synthetase 1

ADAM15

Gene (Entity type)

ENSG00000143537 - ADAM metallopeptidase domain 15

MMRN1

Gene (Entity type)

ENSG00000138722 - multimerin 1

PRCP

Gene (Entity type)

ENSG00000137509 - prolylcarboxypeptidase

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.