GSE140758 MDM2 inhibition 4 v 8 human up (Gene Set)

Dcc Asset:

rummageo gene perturbations.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

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Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with GSE140758_MDM2 inhibition_4_v_8_human_up.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with GSE140758_MDM2 inhibition_4_v_8_human_up.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with GSE140758_MDM2 inhibition_4_v_8_human_up.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with GSE140758_MDM2 inhibition_4_v_8_human_up.

Results found

Linked to

	Label	Description
	GRB2 Gene (Entity type)	ENSG00000177885 - growth factor receptor bound protein 2
	S1PR3 Gene (Entity type)	ENSG00000213694 - sphingosine-1-phosphate receptor 3
	HDAC5 Gene (Entity type)	ENSG00000108840 - histone deacetylase 5
	ATMIN Gene (Entity type)	ENSG00000166454 - ATM interactor
	DTX3L Gene (Entity type)	ENSG00000163840 - deltex E3 ubiquitin ligase 3L
	TRIM24 Gene (Entity type)	ENSG00000122779 - tripartite motif containing 24
	IGFBP7 Gene (Entity type)	ENSG00000163453 - insulin like growth factor binding protein 7
	DYNLL2 Gene (Entity type)	ENSG00000264364 - dynein light chain LC8-type 2
	EGLN1 Gene (Entity type)	ENSG00000135766 - egl-9 family hypoxia inducible factor 1
	MANBA Gene (Entity type)	ENSG00000109323 - mannosidase beta

GRB2

Gene (Entity type)

ENSG00000177885 - growth factor receptor bound protein 2

S1PR3

Gene (Entity type)

ENSG00000213694 - sphingosine-1-phosphate receptor 3

HDAC5

Gene (Entity type)

ENSG00000108840 - histone deacetylase 5

ATMIN

Gene (Entity type)

ENSG00000166454 - ATM interactor

DTX3L

Gene (Entity type)

ENSG00000163840 - deltex E3 ubiquitin ligase 3L

TRIM24

Gene (Entity type)

ENSG00000122779 - tripartite motif containing 24

IGFBP7

Gene (Entity type)

ENSG00000163453 - insulin like growth factor binding protein 7

DYNLL2

Gene (Entity type)

ENSG00000264364 - dynein light chain LC8-type 2

EGLN1

Gene (Entity type)

ENSG00000135766 - egl-9 family hypoxia inducible factor 1

MANBA

Gene (Entity type)

ENSG00000109323 - mannosidase beta

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.