GSE190178 MEK CDK8 inhibition 3 v 4 human up (Gene Set)

Dcc Asset:

rummageo gene perturbations.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with GSE190178_MEK_CDK8 inhibition_3_v_4_human_up.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with GSE190178_MEK_CDK8 inhibition_3_v_4_human_up.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with GSE190178_MEK_CDK8 inhibition_3_v_4_human_up.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with GSE190178_MEK_CDK8 inhibition_3_v_4_human_up.

Results found

Linked to

	Label	Description
	SMAD2 Gene (Entity type)	ENSG00000175387 - SMAD family member 2
	KDM5A Gene (Entity type)	ENSG00000073614 - lysine demethylase 5A
	CHMP2A Gene (Entity type)	ENSG00000130724 - charged multivesicular body protein 2A
	PFDN2 Gene (Entity type)	ENSG00000143256 - prefoldin subunit 2
	GSK3B Gene (Entity type)	ENSG00000082701 - glycogen synthase kinase 3 beta
	NRAS Gene (Entity type)	ENSG00000213281 - NRAS proto-oncogene, GTPase
	GRB2 Gene (Entity type)	ENSG00000177885 - growth factor receptor bound protein 2
	ATMIN Gene (Entity type)	ENSG00000166454 - ATM interactor
	PPP2CB Gene (Entity type)	ENSG00000104695 - protein phosphatase 2 catalytic subunit beta
	NRG1 Gene (Entity type)	ENSG00000157168 - neuregulin 1

SMAD2

Gene (Entity type)

ENSG00000175387 - SMAD family member 2

KDM5A

Gene (Entity type)

ENSG00000073614 - lysine demethylase 5A

CHMP2A

Gene (Entity type)

ENSG00000130724 - charged multivesicular body protein 2A

PFDN2

Gene (Entity type)

ENSG00000143256 - prefoldin subunit 2

GSK3B

Gene (Entity type)

ENSG00000082701 - glycogen synthase kinase 3 beta

NRAS

Gene (Entity type)

ENSG00000213281 - NRAS proto-oncogene, GTPase

GRB2

Gene (Entity type)

ENSG00000177885 - growth factor receptor bound protein 2

ATMIN

Gene (Entity type)

ENSG00000166454 - ATM interactor

PPP2CB

Gene (Entity type)

ENSG00000104695 - protein phosphatase 2 catalytic subunit beta

NRG1

Gene (Entity type)

ENSG00000157168 - neuregulin 1

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.