PLS3 Up (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with PLS3 Up.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with PLS3 Up.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with PLS3 Up.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with PLS3 Up.

Results found

Linked to

	Label	Description
	EIF4E Gene (Entity type)	ENSG00000151247 - eukaryotic translation initiation factor 4E
	SDHD Gene (Entity type)	ENSG00000204370 - succinate dehydrogenase complex subunit D
	PPP2R5C Gene (Entity type)	ENSG00000078304 - protein phosphatase 2 regulatory subunit B'gamma
	NDUFB6 Gene (Entity type)	ENSG00000165264 - NADH:ubiquinone oxidoreductase subunit B6
	E2F5 Gene (Entity type)	ENSG00000133740 - E2F transcription factor 5
	MRS2 Gene (Entity type)	ENSG00000124532 - magnesium transporter MRS2
	YEATS4 Gene (Entity type)	ENSG00000127337 - YEATS domain containing 4
	SDHAF3 Gene (Entity type)	ENSG00000196636 - succinate dehydrogenase complex assembly factor 3
	SIVA1 Gene (Entity type)	ENSG00000184990 - SIVA1 apoptosis inducing factor
	CDC25C Gene (Entity type)	ENSG00000158402 - cell division cycle 25C

EIF4E

Gene (Entity type)

ENSG00000151247 - eukaryotic translation initiation factor 4E

SDHD

Gene (Entity type)

ENSG00000204370 - succinate dehydrogenase complex subunit D

PPP2R5C

Gene (Entity type)

ENSG00000078304 - protein phosphatase 2 regulatory subunit B'gamma

NDUFB6

Gene (Entity type)

ENSG00000165264 - NADH:ubiquinone oxidoreductase subunit B6

E2F5

Gene (Entity type)

ENSG00000133740 - E2F transcription factor 5

MRS2

Gene (Entity type)

ENSG00000124532 - magnesium transporter MRS2

YEATS4

Gene (Entity type)

ENSG00000127337 - YEATS domain containing 4

SDHAF3

Gene (Entity type)

ENSG00000196636 - succinate dehydrogenase complex assembly factor 3

SIVA1

Gene (Entity type)

ENSG00000184990 - SIVA1 apoptosis inducing factor

CDC25C

Gene (Entity type)

ENSG00000158402 - cell division cycle 25C

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Community

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.