GSE221577 PIK3R1 knockout 2 v 0 human dn (Gene Set)

Dcc Asset:

rummageo gene perturbations.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with GSE221577_PIK3R1 knockout_2_v_0_human_dn.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with GSE221577_PIK3R1 knockout_2_v_0_human_dn.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with GSE221577_PIK3R1 knockout_2_v_0_human_dn.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with GSE221577_PIK3R1 knockout_2_v_0_human_dn.

Results found

Linked to

	Label	Description
	HDAC6 Gene (Entity type)	ENSG00000094631 - histone deacetylase 6
	BLVRA Gene (Entity type)	ENSG00000106605 - biliverdin reductase A
	SLC22A5 Gene (Entity type)	ENSG00000197375 - solute carrier family 22 member 5
	F8 Gene (Entity type)	ENSG00000185010 - coagulation factor VIII
	PSEN1 Gene (Entity type)	ENSG00000080815 - presenilin 1
	MANBA Gene (Entity type)	ENSG00000109323 - mannosidase beta
	TGFBR1 Gene (Entity type)	ENSG00000106799 - transforming growth factor beta receptor 1
	USP47 Gene (Entity type)	ENSG00000170242 - ubiquitin specific peptidase 47
	TMEM41B Gene (Entity type)	ENSG00000166471 - transmembrane protein 41B
	PPM1B Gene (Entity type)	ENSG00000138032 - protein phosphatase, Mg2+/Mn2+ dependent 1B

HDAC6

Gene (Entity type)

ENSG00000094631 - histone deacetylase 6

BLVRA

Gene (Entity type)

ENSG00000106605 - biliverdin reductase A

SLC22A5

Gene (Entity type)

ENSG00000197375 - solute carrier family 22 member 5

Gene (Entity type)

ENSG00000185010 - coagulation factor VIII

PSEN1

Gene (Entity type)

ENSG00000080815 - presenilin 1

MANBA

Gene (Entity type)

ENSG00000109323 - mannosidase beta

TGFBR1

Gene (Entity type)

ENSG00000106799 - transforming growth factor beta receptor 1

USP47

Gene (Entity type)

ENSG00000170242 - ubiquitin specific peptidase 47

TMEM41B

Gene (Entity type)

ENSG00000166471 - transmembrane protein 41B

PPM1B

Gene (Entity type)

ENSG00000138032 - protein phosphatase, Mg2+/Mn2+ dependent 1B

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.