GSE195559 NOTCH1 knockout endothelial cell cardiac muscle cell stem cell 6 v 1 human dn (Gene Set)

Dcc Asset:

rummageo gene perturbations.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with GSE195559_NOTCH1 knockout_endothelial cell_cardiac muscle cell_stem cell_6_v_1_human_dn.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with GSE195559_NOTCH1 knockout_endothelial cell_cardiac muscle cell_stem cell_6_v_1_human_dn.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with GSE195559_NOTCH1 knockout_endothelial cell_cardiac muscle cell_stem cell_6_v_1_human_dn.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with GSE195559_NOTCH1 knockout_endothelial cell_cardiac muscle cell_stem cell_6_v_1_human_dn.

Results found

Linked to

	Label	Description
	RPS6 Gene (Entity type)	ENSG00000137154 - ribosomal protein S6
	ADCY3 Gene (Entity type)	ENSG00000138031 - adenylate cyclase 3
	DYNLL2 Gene (Entity type)	ENSG00000264364 - dynein light chain LC8-type 2
	SMC3 Gene (Entity type)	ENSG00000108055 - structural maintenance of chromosomes 3
	HCK Gene (Entity type)	ENSG00000101336 - HCK proto-oncogene, Src family tyrosine kinase
	CHAF1B Gene (Entity type)	ENSG00000159259 - chromatin assembly factor 1 subunit B
	HS3ST3A1 Gene (Entity type)	ENSG00000153976 - heparan sulfate-glucosamine 3-sulfotransferase 3A1
	PAFAH1B3 Gene (Entity type)	ENSG00000079462 - platelet activating factor acetylhydrolase 1b catalytic subunit 3
	PLK4 Gene (Entity type)	ENSG00000142731 - polo like kinase 4
	NR1H3 Gene (Entity type)	ENSG00000025434 - nuclear receptor subfamily 1 group H member 3

RPS6

Gene (Entity type)

ENSG00000137154 - ribosomal protein S6

ADCY3

Gene (Entity type)

ENSG00000138031 - adenylate cyclase 3

DYNLL2

Gene (Entity type)

ENSG00000264364 - dynein light chain LC8-type 2

SMC3

Gene (Entity type)

ENSG00000108055 - structural maintenance of chromosomes 3

HCK

Gene (Entity type)

ENSG00000101336 - HCK proto-oncogene, Src family tyrosine kinase

CHAF1B

Gene (Entity type)

ENSG00000159259 - chromatin assembly factor 1 subunit B

HS3ST3A1

Gene (Entity type)

ENSG00000153976 - heparan sulfate-glucosamine 3-sulfotransferase 3A1

PAFAH1B3

Gene (Entity type)

ENSG00000079462 - platelet activating factor acetylhydrolase 1b catalytic subunit 3

PLK4

Gene (Entity type)

ENSG00000142731 - polo like kinase 4

NR1H3

Gene (Entity type)

ENSG00000025434 - nuclear receptor subfamily 1 group H member 3

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.