C4B Down (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with C4B Down.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with C4B Down.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with C4B Down.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with C4B Down.

Results found

Linked to

	Label	Description
	PUM1 Gene (Entity type)	ENSG00000134644 - pumilio RNA binding family member 1
	C4BPB Gene (Entity type)	ENSG00000123843 - complement component 4 binding protein beta
	HPD Gene (Entity type)	ENSG00000158104 - 4-hydroxyphenylpyruvate dioxygenase
	ITIH3 Gene (Entity type)	ENSG00000162267 - inter-alpha-trypsin inhibitor heavy chain 3
	PIP5K1A Gene (Entity type)	ENSG00000143398 - phosphatidylinositol-4-phosphate 5-kinase type 1 alpha
	NUP43 Gene (Entity type)	ENSG00000120253 - nucleoporin 43
	OVOL2 Gene (Entity type)	ENSG00000125850 - ovo like zinc finger 2
	MRPS35 Gene (Entity type)	ENSG00000061794 - mitochondrial ribosomal protein S35
	NOP2 Gene (Entity type)	ENSG00000111641 - NOP2 nucleolar protein
	CELF1 Gene (Entity type)	ENSG00000149187 - CUGBP Elav-like family member 1

PUM1

Gene (Entity type)

ENSG00000134644 - pumilio RNA binding family member 1

C4BPB

Gene (Entity type)

ENSG00000123843 - complement component 4 binding protein beta

HPD

Gene (Entity type)

ENSG00000158104 - 4-hydroxyphenylpyruvate dioxygenase

ITIH3

Gene (Entity type)

ENSG00000162267 - inter-alpha-trypsin inhibitor heavy chain 3

PIP5K1A

Gene (Entity type)

ENSG00000143398 - phosphatidylinositol-4-phosphate 5-kinase type 1 alpha

NUP43

Gene (Entity type)

ENSG00000120253 - nucleoporin 43

OVOL2

Gene (Entity type)

ENSG00000125850 - ovo like zinc finger 2

MRPS35

Gene (Entity type)

ENSG00000061794 - mitochondrial ribosomal protein S35

NOP2

Gene (Entity type)

ENSG00000111641 - NOP2 nucleolar protein

CELF1

Gene (Entity type)

ENSG00000149187 - CUGBP Elav-like family member 1

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.