HERC5 Down (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with HERC5 Down.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with HERC5 Down.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with HERC5 Down.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with HERC5 Down.

Results found

Linked to

	Label	Description
	HCK Gene (Entity type)	ENSG00000101336 - HCK proto-oncogene, Src family tyrosine kinase
	GTF2H3 Gene (Entity type)	ENSG00000111358 - general transcription factor IIH subunit 3
	PPP2R2A Gene (Entity type)	ENSG00000221914 - protein phosphatase 2 regulatory subunit Balpha
	UBXN7 Gene (Entity type)	ENSG00000163960 - UBX domain protein 7
	PRRG4 Gene (Entity type)	ENSG00000135378 - proline rich and Gla domain 4
	ACYP2 Gene (Entity type)	ENSG00000170634 - acylphosphatase 2
	CSF3R Gene (Entity type)	ENSG00000119535 - colony stimulating factor 3 receptor
	ZNF430 Gene (Entity type)	ENSG00000118620 - zinc finger protein 430
	MRPS33 Gene (Entity type)	ENSG00000090263 - mitochondrial ribosomal protein S33
	LRRC37A3 Gene (Entity type)	ENSG00000176809 - leucine rich repeat containing 37 member A3

HCK

Gene (Entity type)

ENSG00000101336 - HCK proto-oncogene, Src family tyrosine kinase

GTF2H3

Gene (Entity type)

ENSG00000111358 - general transcription factor IIH subunit 3

PPP2R2A

Gene (Entity type)

ENSG00000221914 - protein phosphatase 2 regulatory subunit Balpha

UBXN7

Gene (Entity type)

ENSG00000163960 - UBX domain protein 7

PRRG4

Gene (Entity type)

ENSG00000135378 - proline rich and Gla domain 4

ACYP2

Gene (Entity type)

ENSG00000170634 - acylphosphatase 2

CSF3R

Gene (Entity type)

ENSG00000119535 - colony stimulating factor 3 receptor

ZNF430

Gene (Entity type)

ENSG00000118620 - zinc finger protein 430

MRPS33

Gene (Entity type)

ENSG00000090263 - mitochondrial ribosomal protein S33

LRRC37A3

Gene (Entity type)

ENSG00000176809 - leucine rich repeat containing 37 member A3

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Community

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.