ME2 Down (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with ME2 Down.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with ME2 Down.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with ME2 Down.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with ME2 Down.

Results found

Linked to

	Label	Description
	SMAD2 Gene (Entity type)	ENSG00000175387 - SMAD family member 2
	SMAD4 Gene (Entity type)	ENSG00000141646 - SMAD family member 4
	MEX3C Gene (Entity type)	ENSG00000176624 - mex-3 RNA binding family member C
	VPS4B Gene (Entity type)	ENSG00000119541 - vacuolar protein sorting 4 homolog B
	SOCS6 Gene (Entity type)	ENSG00000170677 - suppressor of cytokine signaling 6
	MYOZ2 Gene (Entity type)	ENSG00000172399 - myozenin 2
	TMEM260 Gene (Entity type)	ENSG00000070269 - transmembrane protein 260
	CXXC1 Gene (Entity type)	ENSG00000154832 - CXXC finger protein 1
	MYH3 Gene (Entity type)	ENSG00000109063 - myosin heavy chain 3
	ST8SIA1 Gene (Entity type)	ENSG00000111728 - ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1

SMAD2

Gene (Entity type)

ENSG00000175387 - SMAD family member 2

SMAD4

Gene (Entity type)

ENSG00000141646 - SMAD family member 4

MEX3C

Gene (Entity type)

ENSG00000176624 - mex-3 RNA binding family member C

VPS4B

Gene (Entity type)

ENSG00000119541 - vacuolar protein sorting 4 homolog B

SOCS6

Gene (Entity type)

ENSG00000170677 - suppressor of cytokine signaling 6

MYOZ2

Gene (Entity type)

ENSG00000172399 - myozenin 2

TMEM260

Gene (Entity type)

ENSG00000070269 - transmembrane protein 260

CXXC1

Gene (Entity type)

ENSG00000154832 - CXXC finger protein 1

MYH3

Gene (Entity type)

ENSG00000109063 - myosin heavy chain 3

ST8SIA1

Gene (Entity type)

ENSG00000111728 - ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.