PKN1 Down (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with PKN1 Down.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with PKN1 Down.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with PKN1 Down.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with PKN1 Down.

Results found

Linked to

	Label	Description
	PRPS1 Gene (Entity type)	ENSG00000147224 - phosphoribosyl pyrophosphate synthetase 1
	PYROXD1 Gene (Entity type)	ENSG00000121350 - pyridine nucleotide-disulphide oxidoreductase domain 1
	WWOX Gene (Entity type)	ENSG00000186153 - WW domain containing oxidoreductase
	PPP1CA Gene (Entity type)	ENSG00000172531 - protein phosphatase 1 catalytic subunit alpha
	MMP13 Gene (Entity type)	ENSG00000137745 - matrix metallopeptidase 13
	MAP9 Gene (Entity type)	ENSG00000164114 - microtubule associated protein 9
	EIF3G Gene (Entity type)	ENSG00000130811 - eukaryotic translation initiation factor 3 subunit G
	UBL5 Gene (Entity type)	ENSG00000198258 - ubiquitin like 5
	SPDEF Gene (Entity type)	ENSG00000124664 - SAM pointed domain containing ETS transcription factor
	CDC37 Gene (Entity type)	ENSG00000105401 - cell division cycle 37, HSP90 cochaperone

PRPS1

Gene (Entity type)

ENSG00000147224 - phosphoribosyl pyrophosphate synthetase 1

PYROXD1

Gene (Entity type)

ENSG00000121350 - pyridine nucleotide-disulphide oxidoreductase domain 1

WWOX

Gene (Entity type)

ENSG00000186153 - WW domain containing oxidoreductase

PPP1CA

Gene (Entity type)

ENSG00000172531 - protein phosphatase 1 catalytic subunit alpha

MMP13

Gene (Entity type)

ENSG00000137745 - matrix metallopeptidase 13

MAP9

Gene (Entity type)

ENSG00000164114 - microtubule associated protein 9

EIF3G

Gene (Entity type)

ENSG00000130811 - eukaryotic translation initiation factor 3 subunit G

UBL5

Gene (Entity type)

ENSG00000198258 - ubiquitin like 5

SPDEF

Gene (Entity type)

ENSG00000124664 - SAM pointed domain containing ETS transcription factor

CDC37

Gene (Entity type)

ENSG00000105401 - cell division cycle 37, HSP90 cochaperone

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Community

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.