ITPA Down (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with ITPA Down.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with ITPA Down.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with ITPA Down.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with ITPA Down.

Results found

Linked to

	Label	Description
	CMTR1 Gene (Entity type)	ENSG00000137200 - cap methyltransferase 1
	ATG4B Gene (Entity type)	ENSG00000168397 - autophagy related 4B cysteine peptidase
	SF3B2 Gene (Entity type)	ENSG00000087365 - splicing factor 3b subunit 2
	MAPK8IP3 Gene (Entity type)	ENSG00000138834 - mitogen-activated protein kinase 8 interacting protein 3
	DDX11 Gene (Entity type)	ENSG00000013573 - DEAD/H-box helicase 11
	DENND4B Gene (Entity type)	ENSG00000198837 - DENN domain containing 4B
	E4F1 Gene (Entity type)	ENSG00000167967 - E4F transcription factor 1
	RANGAP1 Gene (Entity type)	ENSG00000100401 - Ran GTPase activating protein 1
	CD7 Gene (Entity type)	ENSG00000173762 - CD7 molecule
	NOP2 Gene (Entity type)	ENSG00000111641 - NOP2 nucleolar protein

CMTR1

Gene (Entity type)

ENSG00000137200 - cap methyltransferase 1

ATG4B

Gene (Entity type)

ENSG00000168397 - autophagy related 4B cysteine peptidase

SF3B2

Gene (Entity type)

ENSG00000087365 - splicing factor 3b subunit 2

MAPK8IP3

Gene (Entity type)

ENSG00000138834 - mitogen-activated protein kinase 8 interacting protein 3

DDX11

Gene (Entity type)

ENSG00000013573 - DEAD/H-box helicase 11

DENND4B

Gene (Entity type)

ENSG00000198837 - DENN domain containing 4B

E4F1

Gene (Entity type)

ENSG00000167967 - E4F transcription factor 1

RANGAP1

Gene (Entity type)

ENSG00000100401 - Ran GTPase activating protein 1

CD7

Gene (Entity type)

ENSG00000173762 - CD7 molecule

NOP2

Gene (Entity type)

ENSG00000111641 - NOP2 nucleolar protein

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Community

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.