SIRT2 Down (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with SIRT2 Down.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with SIRT2 Down.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with SIRT2 Down.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with SIRT2 Down.

Results found

Linked to

	Label	Description
	HDAC6 Gene (Entity type)	ENSG00000094631 - histone deacetylase 6
	IDH3B Gene (Entity type)	ENSG00000101365 - isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta
	SEC16A Gene (Entity type)	ENSG00000148396 - SEC16 homolog A, endoplasmic reticulum export factor
	RBM6 Gene (Entity type)	ENSG00000004534 - RNA binding motif protein 6
	FANCL Gene (Entity type)	ENSG00000115392 - FA complementation group L
	KCNMB1 Gene (Entity type)	ENSG00000145936 - potassium calcium-activated channel subfamily M regulatory beta subunit 1
	RPA1 Gene (Entity type)	ENSG00000132383 - replication protein A1
	UGT2B4 Gene (Entity type)	ENSG00000156096 - UDP glucuronosyltransferase family 2 member B4
	PNPLA6 Gene (Entity type)	ENSG00000032444 - patatin like domain 6, lysophospholipase
	KHK Gene (Entity type)	ENSG00000138030 - ketohexokinase

HDAC6

Gene (Entity type)

ENSG00000094631 - histone deacetylase 6

IDH3B

Gene (Entity type)

ENSG00000101365 - isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta

SEC16A

Gene (Entity type)

ENSG00000148396 - SEC16 homolog A, endoplasmic reticulum export factor

RBM6

Gene (Entity type)

ENSG00000004534 - RNA binding motif protein 6

FANCL

Gene (Entity type)

ENSG00000115392 - FA complementation group L

KCNMB1

Gene (Entity type)

ENSG00000145936 - potassium calcium-activated channel subfamily M regulatory beta subunit 1

RPA1

Gene (Entity type)

ENSG00000132383 - replication protein A1

UGT2B4

Gene (Entity type)

ENSG00000156096 - UDP glucuronosyltransferase family 2 member B4

PNPLA6

Gene (Entity type)

ENSG00000032444 - patatin like domain 6, lysophospholipase

KHK

Gene (Entity type)

ENSG00000138030 - ketohexokinase

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Community

Resources

@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.