ITM2C Down (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with ITM2C Down.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with ITM2C Down.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with ITM2C Down.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with ITM2C Down.

Results found

Linked to

	Label	Description
	GRB2 Gene (Entity type)	ENSG00000177885 - growth factor receptor bound protein 2
	PSMD4 Gene (Entity type)	ENSG00000159352 - proteasome 26S subunit ubiquitin receptor, non-ATPase 4
	ZNF706 Gene (Entity type)	ENSG00000120963 - zinc finger protein 706
	EPYC Gene (Entity type)	ENSG00000083782 - epiphycan
	TTC9 Gene (Entity type)	ENSG00000133985 - tetratricopeptide repeat domain 9
	TRAPPC6A Gene (Entity type)	ENSG00000007255 - trafficking protein particle complex subunit 6A
	LRRC32 Gene (Entity type)	ENSG00000137507 - leucine rich repeat containing 32
	ARC Gene (Entity type)	ENSG00000198576 - activity regulated cytoskeleton associated protein
	ARHGAP25 Gene (Entity type)	ENSG00000163219 - Rho GTPase activating protein 25
	VTI1B Gene (Entity type)	ENSG00000100568 - vesicle transport through interaction with t-SNAREs 1B

GRB2

Gene (Entity type)

ENSG00000177885 - growth factor receptor bound protein 2

PSMD4

Gene (Entity type)

ENSG00000159352 - proteasome 26S subunit ubiquitin receptor, non-ATPase 4

ZNF706

Gene (Entity type)

ENSG00000120963 - zinc finger protein 706

EPYC

Gene (Entity type)

ENSG00000083782 - epiphycan

TTC9

Gene (Entity type)

ENSG00000133985 - tetratricopeptide repeat domain 9

TRAPPC6A

Gene (Entity type)

ENSG00000007255 - trafficking protein particle complex subunit 6A

LRRC32

Gene (Entity type)

ENSG00000137507 - leucine rich repeat containing 32

ARC

Gene (Entity type)

ENSG00000198576 - activity regulated cytoskeleton associated protein

ARHGAP25

Gene (Entity type)

ENSG00000163219 - Rho GTPase activating protein 25

VTI1B

Gene (Entity type)

ENSG00000100568 - vesicle transport through interaction with t-SNAREs 1B

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.