COG2 Down (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with COG2 Down.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with COG2 Down.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with COG2 Down.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with COG2 Down.

Results found

Linked to

	Label	Description
	PAFAH1B3 Gene (Entity type)	ENSG00000079462 - platelet activating factor acetylhydrolase 1b catalytic subunit 3
	RUVBL2 Gene (Entity type)	ENSG00000183207 - RuvB like AAA ATPase 2
	RPA2 Gene (Entity type)	ENSG00000117748 - replication protein A2
	ZDHHC4 Gene (Entity type)	ENSG00000136247 - zDHHC palmitoyltransferase 4
	SDHAF3 Gene (Entity type)	ENSG00000196636 - succinate dehydrogenase complex assembly factor 3
	FBXO3 Gene (Entity type)	ENSG00000110429 - F-box protein 3
	COA3 Gene (Entity type)	ENSG00000183978 - cytochrome c oxidase assembly factor 3
	IGSF6 Gene (Entity type)	ENSG00000140749 - immunoglobulin superfamily member 6
	GBA3 Gene (Entity type)	ENSG00000249948 - glucosylceramidase beta 3 (gene/pseudogene)
	RSAD1 Gene (Entity type)	ENSG00000136444 - radical S-adenosyl methionine domain containing 1

PAFAH1B3

Gene (Entity type)

ENSG00000079462 - platelet activating factor acetylhydrolase 1b catalytic subunit 3

RUVBL2

Gene (Entity type)

ENSG00000183207 - RuvB like AAA ATPase 2

RPA2

Gene (Entity type)

ENSG00000117748 - replication protein A2

ZDHHC4

Gene (Entity type)

ENSG00000136247 - zDHHC palmitoyltransferase 4

SDHAF3

Gene (Entity type)

ENSG00000196636 - succinate dehydrogenase complex assembly factor 3

FBXO3

Gene (Entity type)

ENSG00000110429 - F-box protein 3

COA3

Gene (Entity type)

ENSG00000183978 - cytochrome c oxidase assembly factor 3

IGSF6

Gene (Entity type)

ENSG00000140749 - immunoglobulin superfamily member 6

GBA3

Gene (Entity type)

ENSG00000249948 - glucosylceramidase beta 3 (gene/pseudogene)

RSAD1

Gene (Entity type)

ENSG00000136444 - radical S-adenosyl methionine domain containing 1

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.