GSE179235 MEK NRAS inhibition 4 v 7 human dn (Gene Set)

Dcc Asset:

rummageo gene perturbations.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with GSE179235_MEK_NRAS inhibition_4_v_7_human_dn.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with GSE179235_MEK_NRAS inhibition_4_v_7_human_dn.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with GSE179235_MEK_NRAS inhibition_4_v_7_human_dn.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with GSE179235_MEK_NRAS inhibition_4_v_7_human_dn.

Results found

Linked to

	Label	Description
	PTPN12 Gene (Entity type)	ENSG00000127947 - protein tyrosine phosphatase non-receptor type 12
	ROCK2 Gene (Entity type)	ENSG00000134318 - Rho associated coiled-coil containing protein kinase 2
	NRG1 Gene (Entity type)	ENSG00000157168 - neuregulin 1
	HS3ST3A1 Gene (Entity type)	ENSG00000153976 - heparan sulfate-glucosamine 3-sulfotransferase 3A1
	NR1H3 Gene (Entity type)	ENSG00000025434 - nuclear receptor subfamily 1 group H member 3
	NFIC Gene (Entity type)	ENSG00000141905 - nuclear factor I C
	CLMP Gene (Entity type)	ENSG00000166250 - CXADR like cell adhesion molecule
	TMEM43 Gene (Entity type)	ENSG00000170876 - transmembrane protein 43
	CAD Gene (Entity type)	ENSG00000084774 - carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
	IGF2BP1 Gene (Entity type)	ENSG00000159217 - insulin like growth factor 2 mRNA binding protein 1

PTPN12

Gene (Entity type)

ENSG00000127947 - protein tyrosine phosphatase non-receptor type 12

ROCK2

Gene (Entity type)

ENSG00000134318 - Rho associated coiled-coil containing protein kinase 2

NRG1

Gene (Entity type)

ENSG00000157168 - neuregulin 1

HS3ST3A1

Gene (Entity type)

ENSG00000153976 - heparan sulfate-glucosamine 3-sulfotransferase 3A1

NR1H3

Gene (Entity type)

ENSG00000025434 - nuclear receptor subfamily 1 group H member 3

NFIC

Gene (Entity type)

ENSG00000141905 - nuclear factor I C

CLMP

Gene (Entity type)

ENSG00000166250 - CXADR like cell adhesion molecule

TMEM43

Gene (Entity type)

ENSG00000170876 - transmembrane protein 43

CAD

Gene (Entity type)

ENSG00000084774 - carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase

IGF2BP1

Gene (Entity type)

ENSG00000159217 - insulin like growth factor 2 mRNA binding protein 1

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.