GSE118490 1 V 0 TRAMETINIB HUMAN UP (Gene Set)

Dcc Asset:

RummaGEO DrugPerturbations 2025.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with GSE118490 1 V 0 TRAMETINIB HUMAN UP.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with GSE118490 1 V 0 TRAMETINIB HUMAN UP.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with GSE118490 1 V 0 TRAMETINIB HUMAN UP.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with GSE118490 1 V 0 TRAMETINIB HUMAN UP.

Results found

Linked to

	Label	Description
	SMAD2 Gene (Entity type)	ENSG00000175387 - SMAD family member 2
	KDM5A Gene (Entity type)	ENSG00000073614 - lysine demethylase 5A
	PPP2R2C Gene (Entity type)	ENSG00000074211 - protein phosphatase 2 regulatory subunit Bgamma
	RBCK1 Gene (Entity type)	ENSG00000125826 - RANBP2-type and C3HC4-type zinc finger containing 1
	DTX3L Gene (Entity type)	ENSG00000163840 - deltex E3 ubiquitin ligase 3L
	NRG1 Gene (Entity type)	ENSG00000157168 - neuregulin 1
	PTGR1 Gene (Entity type)	ENSG00000106853 - prostaglandin reductase 1
	SIK3 Gene (Entity type)	ENSG00000160584 - SIK family kinase 3
	LTBR Gene (Entity type)	ENSG00000111321 - lymphotoxin beta receptor
	NSF Gene (Entity type)	ENSG00000073969 - N-ethylmaleimide sensitive factor, vesicle fusing ATPase

SMAD2

Gene (Entity type)

ENSG00000175387 - SMAD family member 2

KDM5A

Gene (Entity type)

ENSG00000073614 - lysine demethylase 5A

PPP2R2C

Gene (Entity type)

ENSG00000074211 - protein phosphatase 2 regulatory subunit Bgamma

RBCK1

Gene (Entity type)

ENSG00000125826 - RANBP2-type and C3HC4-type zinc finger containing 1

DTX3L

Gene (Entity type)

ENSG00000163840 - deltex E3 ubiquitin ligase 3L

NRG1

Gene (Entity type)

ENSG00000157168 - neuregulin 1

PTGR1

Gene (Entity type)

ENSG00000106853 - prostaglandin reductase 1

SIK3

Gene (Entity type)

ENSG00000160584 - SIK family kinase 3

LTBR

Gene (Entity type)

ENSG00000111321 - lymphotoxin beta receptor

NSF

Gene (Entity type)

ENSG00000073969 - N-ethylmaleimide sensitive factor, vesicle fusing ATPase

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.