PLAU Down (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with PLAU Down.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with PLAU Down.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with PLAU Down.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with PLAU Down.

Results found

Linked to

	Label	Description
	NFATC1 Gene (Entity type)	ENSG00000131196 - nuclear factor of activated T cells 1
	PTBP2 Gene (Entity type)	ENSG00000117569 - polypyrimidine tract binding protein 2
	AGA Gene (Entity type)	ENSG00000038002 - aspartylglucosaminidase
	NSL1 Gene (Entity type)	ENSG00000117697 - NSL1 component of MIS12 kinetochore complex
	TM4SF20 Gene (Entity type)	ENSG00000168955 - transmembrane 4 L six family member 20
	TNFRSF25 Gene (Entity type)	ENSG00000215788 - TNF receptor superfamily member 25
	HSD17B8 Gene (Entity type)	ENSG00000204228 - hydroxysteroid 17-beta dehydrogenase 8
	IGSF6 Gene (Entity type)	ENSG00000140749 - immunoglobulin superfamily member 6
	LSM6 Gene (Entity type)	ENSG00000164167 - LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated
	LIN28A Gene (Entity type)	ENSG00000131914 - lin-28 RNA binding posttranscriptional regulator A

NFATC1

Gene (Entity type)

ENSG00000131196 - nuclear factor of activated T cells 1

PTBP2

Gene (Entity type)

ENSG00000117569 - polypyrimidine tract binding protein 2

AGA

Gene (Entity type)

ENSG00000038002 - aspartylglucosaminidase

NSL1

Gene (Entity type)

ENSG00000117697 - NSL1 component of MIS12 kinetochore complex

TM4SF20

Gene (Entity type)

ENSG00000168955 - transmembrane 4 L six family member 20

TNFRSF25

Gene (Entity type)

ENSG00000215788 - TNF receptor superfamily member 25

HSD17B8

Gene (Entity type)

ENSG00000204228 - hydroxysteroid 17-beta dehydrogenase 8

IGSF6

Gene (Entity type)

ENSG00000140749 - immunoglobulin superfamily member 6

LSM6

Gene (Entity type)

ENSG00000164167 - LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated

LIN28A

Gene (Entity type)

ENSG00000131914 - lin-28 RNA binding posttranscriptional regulator A

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Community

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.