GSE226249 pirfenidone HL 2 v 4 human up (Gene Set)

Dcc Asset:

rummageo chemical perturbations.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with GSE226249_pirfenidone_HL_2_v_4_human_up.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with GSE226249_pirfenidone_HL_2_v_4_human_up.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with GSE226249_pirfenidone_HL_2_v_4_human_up.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with GSE226249_pirfenidone_HL_2_v_4_human_up.

Results found

Linked to

	Label	Description
	CPNE3 Gene (Entity type)	ENSG00000085719 - copine 3
	EXT2 Gene (Entity type)	ENSG00000151348 - exostosin glycosyltransferase 2
	PLCG1 Gene (Entity type)	ENSG00000124181 - phospholipase C gamma 1
	GRB2 Gene (Entity type)	ENSG00000177885 - growth factor receptor bound protein 2
	MEGF9 Gene (Entity type)	ENSG00000106780 - multiple EGF like domains 9
	ERN1 Gene (Entity type)	ENSG00000178607 - endoplasmic reticulum to nucleus signaling 1
	PSMD4 Gene (Entity type)	ENSG00000159352 - proteasome 26S subunit ubiquitin receptor, non-ATPase 4
	MAP2K3 Gene (Entity type)	ENSG00000034152 - mitogen-activated protein kinase kinase 3
	DYNLL2 Gene (Entity type)	ENSG00000264364 - dynein light chain LC8-type 2
	RAB7A Gene (Entity type)	ENSG00000075785 - RAB7A, member RAS oncogene family

CPNE3

Gene (Entity type)

ENSG00000085719 - copine 3

EXT2

Gene (Entity type)

ENSG00000151348 - exostosin glycosyltransferase 2

PLCG1

Gene (Entity type)

ENSG00000124181 - phospholipase C gamma 1

GRB2

Gene (Entity type)

ENSG00000177885 - growth factor receptor bound protein 2

MEGF9

Gene (Entity type)

ENSG00000106780 - multiple EGF like domains 9

ERN1

Gene (Entity type)

ENSG00000178607 - endoplasmic reticulum to nucleus signaling 1

PSMD4

Gene (Entity type)

ENSG00000159352 - proteasome 26S subunit ubiquitin receptor, non-ATPase 4

MAP2K3

Gene (Entity type)

ENSG00000034152 - mitogen-activated protein kinase kinase 3

DYNLL2

Gene (Entity type)

ENSG00000264364 - dynein light chain LC8-type 2

RAB7A

Gene (Entity type)

ENSG00000075785 - RAB7A, member RAS oncogene family

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.