PFKM Down (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with PFKM Down.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with PFKM Down.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with PFKM Down.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with PFKM Down.

Results found

Linked to

	Label	Description
	PPP1CC Gene (Entity type)	ENSG00000186298 - protein phosphatase 1 catalytic subunit gamma
	HINT1 Gene (Entity type)	ENSG00000169567 - histidine triad nucleotide binding protein 1
	MIF Gene (Entity type)	ENSG00000240972 - macrophage migration inhibitory factor
	HIPK1 Gene (Entity type)	ENSG00000163349 - homeodomain interacting protein kinase 1
	TDG Gene (Entity type)	ENSG00000139372 - thymine DNA glycosylase
	ECH1 Gene (Entity type)	ENSG00000104823 - enoyl-CoA hydratase 1
	CDK17 Gene (Entity type)	ENSG00000059758 - cyclin dependent kinase 17
	KNTC1 Gene (Entity type)	ENSG00000184445 - kinetochore associated 1
	APPL2 Gene (Entity type)	ENSG00000136044 - adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2
	MIA3 Gene (Entity type)	ENSG00000154305 - MIA SH3 domain ER export factor 3

PPP1CC

Gene (Entity type)

ENSG00000186298 - protein phosphatase 1 catalytic subunit gamma

HINT1

Gene (Entity type)

ENSG00000169567 - histidine triad nucleotide binding protein 1

MIF

Gene (Entity type)

ENSG00000240972 - macrophage migration inhibitory factor

HIPK1

Gene (Entity type)

ENSG00000163349 - homeodomain interacting protein kinase 1

TDG

Gene (Entity type)

ENSG00000139372 - thymine DNA glycosylase

ECH1

Gene (Entity type)

ENSG00000104823 - enoyl-CoA hydratase 1

CDK17

Gene (Entity type)

ENSG00000059758 - cyclin dependent kinase 17

KNTC1

Gene (Entity type)

ENSG00000184445 - kinetochore associated 1

APPL2

Gene (Entity type)

ENSG00000136044 - adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2

MIA3

Gene (Entity type)

ENSG00000154305 - MIA SH3 domain ER export factor 3

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Community

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.