RIT1 Down (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with RIT1 Down.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with RIT1 Down.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with RIT1 Down.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with RIT1 Down.

Results found

Linked to

	Label	Description
	PPP2CB Gene (Entity type)	ENSG00000104695 - protein phosphatase 2 catalytic subunit beta
	CDK7 Gene (Entity type)	ENSG00000134058 - cyclin dependent kinase 7
	NCK2 Gene (Entity type)	ENSG00000071051 - NCK adaptor protein 2
	RAB1A Gene (Entity type)	ENSG00000138069 - RAB1A, member RAS oncogene family
	REL Gene (Entity type)	ENSG00000162924 - REL proto-oncogene, NF-kB subunit
	RHEB Gene (Entity type)	ENSG00000106615 - Ras homolog, mTORC1 binding
	LRRC1 Gene (Entity type)	ENSG00000137269 - leucine rich repeat containing 1
	POLR2K Gene (Entity type)	ENSG00000147669 - RNA polymerase II, I and III subunit K
	CFAP20 Gene (Entity type)	ENSG00000070761 - cilia and flagella associated protein 20
	SRSF10 Gene (Entity type)	ENSG00000188529 - serine and arginine rich splicing factor 10

PPP2CB

Gene (Entity type)

ENSG00000104695 - protein phosphatase 2 catalytic subunit beta

CDK7

Gene (Entity type)

ENSG00000134058 - cyclin dependent kinase 7

NCK2

Gene (Entity type)

ENSG00000071051 - NCK adaptor protein 2

RAB1A

Gene (Entity type)

ENSG00000138069 - RAB1A, member RAS oncogene family

REL

Gene (Entity type)

ENSG00000162924 - REL proto-oncogene, NF-kB subunit

RHEB

Gene (Entity type)

ENSG00000106615 - Ras homolog, mTORC1 binding

LRRC1

Gene (Entity type)

ENSG00000137269 - leucine rich repeat containing 1

POLR2K

Gene (Entity type)

ENSG00000147669 - RNA polymerase II, I and III subunit K

CFAP20

Gene (Entity type)

ENSG00000070761 - cilia and flagella associated protein 20

SRSF10

Gene (Entity type)

ENSG00000188529 - serine and arginine rich splicing factor 10

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.