VSIR Down (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with VSIR Down.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with VSIR Down.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with VSIR Down.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with VSIR Down.

Results found

Linked to

	Label	Description
	SMAD2 Gene (Entity type)	ENSG00000175387 - SMAD family member 2
	ALG5 Gene (Entity type)	ENSG00000120697 - ALG5 dolichyl-phosphate beta-glucosyltransferase
	CLDN5 Gene (Entity type)	ENSG00000184113 - claudin 5
	NSL1 Gene (Entity type)	ENSG00000117697 - NSL1 component of MIS12 kinetochore complex
	TSNAX Gene (Entity type)	ENSG00000116918 - translin associated factor X
	ZNF329 Gene (Entity type)	ENSG00000181894 - zinc finger protein 329
	TPST1 Gene (Entity type)	ENSG00000169902 - tyrosylprotein sulfotransferase 1
	MKKS Gene (Entity type)	ENSG00000125863 - MKKS centrosomal shuttling protein
	METTL5 Gene (Entity type)	ENSG00000138382 - methyltransferase 5, N6-adenosine
	EIF4E2 Gene (Entity type)	ENSG00000135930 - eukaryotic translation initiation factor 4E family member 2

SMAD2

Gene (Entity type)

ENSG00000175387 - SMAD family member 2

ALG5

Gene (Entity type)

ENSG00000120697 - ALG5 dolichyl-phosphate beta-glucosyltransferase

CLDN5

Gene (Entity type)

ENSG00000184113 - claudin 5

NSL1

Gene (Entity type)

ENSG00000117697 - NSL1 component of MIS12 kinetochore complex

TSNAX

Gene (Entity type)

ENSG00000116918 - translin associated factor X

ZNF329

Gene (Entity type)

ENSG00000181894 - zinc finger protein 329

TPST1

Gene (Entity type)

ENSG00000169902 - tyrosylprotein sulfotransferase 1

MKKS

Gene (Entity type)

ENSG00000125863 - MKKS centrosomal shuttling protein

METTL5

Gene (Entity type)

ENSG00000138382 - methyltransferase 5, N6-adenosine

EIF4E2

Gene (Entity type)

ENSG00000135930 - eukaryotic translation initiation factor 4E family member 2

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.